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5.B.5.1.1
The multihaem c-type cytochrome quinol:Fe3+ /Mn3 /4+ oxidoreductase, Cym/Mtr (Shi et al., 2007).  MtrABC is composed of two decahaem cytochromes (MtrA & B) brought together inside a transmembrane β-porin (MtrC) to transport electrons across the outer membrane to mineral based electron acceptors (White et al. 2012).  Conduction through MtrCAB directly to Fe(III) oxides occurs both in vitro in liposomes and in vivo, allowing anaerobic, solid-phase iron respiration (White et al. 2013). MtrC interacts with the surface of MtrAB, extending ∼70 Å from the membrane surface and allowing the terminal hemes to interact with both MtrAB and an extracellular acceptor. MtrA fully extends through the length of MtrB, with ∼30 Å being exposed into the periplasm. MtrCAB can reduce Fe(III) citrate with STC as an electron donor, disclosing a direct interaction between MtrCAB and STC (Edwards et al. 2018). MtrC, but not UndA (a paralog of MtrC of 843 aas; F8UWD6), appears to be the primary reductase of flavins to ensure fast indirect extracellular electron transfer (EET), which plays a crucial role in microbial fuel cell (MFC) electricity generation in Shewanella putrefaciens CN32 (Wu et al. 2018). The dimensions of MtrAB are approximately 105 x 60 x 35 Å and approximately 170 x 60 x 45 Å for MtrCAB. Their shapes suggest that MtrC interacts with the surface of MtrAB, extending approximately 70 Å from the membrane surface and allowing the terminal hemes to interact with both MtrAB and an extracellular acceptor. MtrA fully extends through the length of MtrB, with approximately 30 Å being exposed into the periplasm (Edwards et al. 2018).

Accession Number:Q8EG34
Protein Name:MtrB
Length:671
Molecular Weight:71237.00
Species:Shewanella oneidensis [70863]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Electrons

Cross database links:

HEGENOM: HBG679086
RefSeq: NP_717387.1   
Entrez Gene ID: 1169552   
BioCyc: SONE211586:SO_1778-MONOMER   
KEGG: son:SO_1778   

References (1)

[1] “Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.”  Heidelberg J.F.et.al.   12368813
Structure:
4LM8     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMNAQKSKIA LLLAASAVTM ALTGCGGSDG NNGNDGSDGG EPAGSIQTLN LDITKVSYEN 
61:	GAPMVTVFAT NEADMPVIGL ANLEIKKALQ LIPEGATGPG NSANWQGLGS SKSYVDNKNG 
121:	SYTFKFDAFD SNKVFNAQLT QRFNVVSAAG KLADGTTVPV AEMVEDFDGQ GNAPQYTKNI 
181:	VSHEVCASCH VEGEKIYHQA TEVETCISCH TQEFADGRGK PHVAFSHLIH NVHNANKAWG 
241:	KDNKIPTVAQ NIVQDNCQVC HVESDMLTEA KNWSRIPTME VCSSCHVDID FAAGKGHSQQ 
301:	LDNSNCIACH NSDWTAELHT AKTTATKNLI NQYGIETTST INTETKAATI SVQVVDANGT 
361:	AVDLKTILPK VQRLEIITNV GPNNATLGYS GKDSIFAIKN GALDPKATIN DAGKLVYTTT 
421:	KDLKLGQNGA DSDTAFSFVG WSMCSSEGKF VDCADPAFDG VDVTKYTGMK ADLAFATLSG 
481:	KAPSTRHVDS VNMTACANCH TAEFEIHKGK QHAGFVMTEQ LSHTQDANGK AIVGLDACVT 
541:	CHTPDGTYSF ANRGALELKL HKKHVEDAYG LIGGNCASCH SDFNLESFKK KGALNTAAAA 
601:	DKTGLYSTPI TATCTTCHTV GSQYMVHTKE TLESFGAVVD GTKDDATSAA QSETCFYCHT 
661:	PTVADHTKVK M