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4.A.2.1.9
The FrzABC PTS putative transporter (promotes bacterial fitness under stress conditions and promotes fimbrial (fim) gene expression indirectly (Rouquet et al., 2009). Might transport D-tagatose, D-psicose and/or D-sorbose, or a disaccharide of these (Rouquet et al. 2009); involved in environmental sensing, host adaptation and virulence (Patron et al. 2015).

Accession Number:Q8FC73
Protein Name:PTS system, fructose-like-2 IIB component 1
Length:104
Molecular Weight:11244.00
Species:Escherichia coli O6 [217992]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Tagatose, psicose, Sorbose

Cross database links:

HEGENOM: HBG564028
RefSeq: NP_756348.1   
Entrez Gene ID: 1038289   
Pfam: PF02302   
KEGG: ecc:c4486   

Gene Ontology

GO:0016020 C:membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (1)

[1] “Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.”  Welch R.A.et.al.   12471157

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNIVCVAACT AGIAHTYIAR EKLIKGAKAL GHTIKVETQG TIGTENELQA ADISAADVVI 
61:	LAVDVKIKGE ERFTNKRIVR VKTEIVIKSP VQFLEKVEKS LGNK