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3.A.1.106.3
The dimeric multidrug resistance exporter, ABC1/2 (exports the peptide antimicrobials, nisin and polymyxin; (Margolles et al., 2006) (both ABC1 and ABC2 also show striking similarity to family 3.A.1.117).

Accession Number:Q8G7R7
Protein Name:Probable permease protein of ABC transporter system
Length:602
Molecular Weight:68130.00
Species:Bifidobacterium longum [216816]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Nisin, Polymyxin

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_695398.1   
Entrez Gene ID: 1023042   
Pfam: PF00664    PF00005   
BioCyc: BLON206672:BL0180-MONOMER   
KEGG: blo:BL0180   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (1)

[1] “The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract.”  Schell M.A.et.al.   12381787

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MAQRNTYRED EELEEQINFR DILRVGKYLK PYMAQVARIL VVVISMSCIV VAVPYLTKIM 
61:	IDEAIPNKDL GKLGILAVIL AALIVLYEFG LRYRTVAITR VGQLMLKDMR RDIFTHIQTL 
121:	PFSYFDSRPH GKILIRVVNY VNTLSDTLSS GLINVISDVF TFVITLIVMF VIDWQLALWS 
181:	LILFPVLIIW VRVLQIFQRR AFQKLSNKQS NLNAYIHESI AGVKTTQTFA QEQAQFRTFQ 
241:	EQQGEVRSAW MHAVHIQFLM WPGVQTISVM TISFIYFVGV MGFGGVNVTT GVLIAFVGYA 
301:	NNFWNPVINI GNFYNQLITC SAYLERIFET LDVTPEIRNK PDAADLPQIR GRVDFNDVVF 
361:	RYEKDGRNIL NLVDFHVEPG RTIALVGPTG AGKTTIINLL SRFYDVSEGS VTIDGYDVRD 
421:	VTLASLRRQM GVMLQDTFIF SGNVRENIRY GKLDATDEEI EAAAKAVHAH EFIMELPDGY 
481:	DTVVEERGST LSAGQRQLIA FARVLLADPR ILILDEATSN IDTRTEEALQ AGLQHLLKGR 
541:	TSFIIAHRLS TIENADEIFY IDHGQIVEHG SHAQLLAAKG AYYRLYESQY AMIRVASGAP 
601:	EE