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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007).

Accession Number:Q8GD02
Protein Name:TadV
Length:142
Molecular Weight:15818.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate proteins

Cross database links:

Pfam: PF01478   

Gene Ontology

GO:0016020 C:membrane
GO:0004190 F:aspartic-type endopeptidase activity

References (2)

[1] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[2] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNWVINALVI ITLLLLITLS VTDIRSRLIS NRVVLFLLFV IVPFSLLKYQ TIFVIPALCT 
61:	LIIGFLLFSL HFIGAGDVKL VSVLMLAVPS DEIFSFFFFT TFAGLGLIII GWLFFRKSIK 
121:	ENGLPYGVAI SLGFMINLAL SN