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3.A.1.12.11
The glycine betaine uptake porter, GbpABCD (Saum et al., 2009).

Accession Number:Q8Q042
Protein Name:Glycine betaine transport system, permease protein
Length:220
Molecular Weight:23615.00
Species:Methanosarcina mazei [2209]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Glycine betaine

Cross database links:

HEGENOM: HBG592565
RefSeq: NP_632320.1   
Entrez Gene ID: 1478638   
Pfam: PF00528   
BioCyc: MMAZ192952:MM0296-MONOMER   
KEGG: mma:MM_0296   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.”  Deppenmeier U.et.al.   12125824

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIIEGLNDFT AEIIRVWNTQ MLSLRTVEHL YMFFFALFFS ILIGVVTGVL TYRNQKLAGP 
61:	VLNSLNVVET VPDVALLVLL LPIFGIGAAP TIVASILYSI LPIARDTYTG LSNVPREYIE 
121:	IAEALGLTPR EVLFKVRFPL SLPLIAGGVR IAVVFTMGVV TLGGLIAAGG LGAALQNGIQ 
181:	LYDMGTILVT GAWVGLLAVL LDGIAGIIEK ILKARYGTWS