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3.A.1.122.3
The enterocin AS-48 exporter, As-48FGH

Accession Number:Q8RKC0
Protein Name:As-48H
Length:399
Molecular Weight:44054.00
Species:Enterococcus faecalis subsp. liquefaciens [44244]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Enterocin

Cross database links:

Pfam: PF02687   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (2)

[1] “Analysis of the gene cluster involved in production and immunity of the peptide antibiotic AS-48 in Enterococcus faecalis.”  Martinez-Bueno M.et.al.   9484890
[2] “Characterization of a new operon, as-48EFGH, from the as-48 gene cluster involved in immunity to enterocin AS-48.”  Diaz M.et.al.   12571051

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MNLYVNMRSA WKAIKNNRKR SVLTMIGIII GISSVITILA IGRGFERDTV KNLTKSDSKN 
61:	VEVQLNFTPS DTSLYDTNTK FFQDVDLSTV RNVEGVKKAD YSKIDEEQIY KDLSIRGNKK 
121:	NKQIKLIDSE GKKVSIGRNL TGQDSELLNK VATIDSVTAK ELFNTPERAL GKGIEIEQEL 
181:	FRVVGVFPGE EPDNLFSLSN TNIEIPKDTY HYYFKSEKNT SSLTLTLEEG VKPDKVTSKV 
241:	IKQLKEKGSL RHLGEYEVLD TAMLTKGIGQ ILSTITYFIT AVAGISLFIA GVGVMNMMYI 
301:	SVSERTKEIG IRRALGATRK SIMLQFLLEG LILTISGGII GYLLGMVFAY GIGSLIKVHV 
361:	SVDLFTIILA VGVSSVIGLV FSVMPASEAA KKDLIDILR