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3.A.1.122.3
The enterocin AS-48 exporter, As-48FGH

Accession Number:Q8RKC1
Protein Name:As-48G
Length:227
Molecular Weight:25702.00
Species:Enterococcus faecalis subsp. liquefaciens [44244]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Enterocin

Cross database links:

Pfam: PF00005   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (2)

[1] “Analysis of the gene cluster involved in production and immunity of the peptide antibiotic AS-48 in Enterococcus faecalis.”  Martinez-Bueno M.et.al.   9484890
[2] “Characterization of a new operon, as-48EFGH, from the as-48 gene cluster involved in immunity to enterocin AS-48.”  Diaz M.et.al.   12571051

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MIELNKINKY YANEEESLHV LKDIHLSIKK GEMIAIMGPS GSGKSTLINL LGFIDRKFEG 
61:	EYLFEGRSLV NTADDILSKI RNQTVGFIFQ NFSLIESNTV YENVELPLLY NGVSPFKTKE 
121:	KVFSVLDRVG LKGKEYKYPK QLSGGQQQRV AIARALINHP KFIIADEPTG ALDTHTSEEI 
181:	MQLFTTLNKE DDVTLIMVTH NPEVVPYCHR LITIRDGAII EDKELVQ