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3.A.1.6.5
Tungsten (KM=20pM)/molybdate (KM=10nM) porter (Bevers et al., 2006)

Accession Number:Q8U4K3
Protein Name:WtpC
Length:344
Molecular Weight:38436.00
Species:Pyrococcus furiosus [2261]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Molybdate, Tungstate

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_577811.1   
Entrez Gene ID: 1467911   
Pfam: PF00005    PF03459   
KEGG: pfu:PF0082   

Gene Ontology

GO:0043190 C:ATP-binding cassette (ABC) transporter complex
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0015412 F:molybdate transmembrane-transporting ATPase...
GO:0030151 F:molybdenum ion binding
GO:0006810 P:transport

References (1)

[1] “Tungsten transport protein A (WtpA) in Pyrococcus furiosus: the first member of a new class of tungstate and molybdate transporters.”  Bevers L.E.et.al.   16952940

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLEVQGISKK WKDFHLKDIS FSVMDGEYFI VLGPSGAGKT VLLEIIAGII PPDGGKVLLD 
61:	GKDITLLPPE KRGIAYVPQN YALFPNMSVF DNIAFGLKVR RVPRSEIEKR VLEISEVLGI 
121:	RHLLHRKPRT LSGGEQQRVA VARALVIEPE IILLDEPFAN LDVQIRSRLI NEMKRWRREL 
181:	GFTAIHVTHS FEEALALGDR VGIMLNGKLV QVGEIREVFS RPNSEEVAKF LGFENIIEGI 
241:	ADGRVLHVGK LRIELPLEAK GRVRIGIRPE DILISTERIK TSARNVFKAK VEAIEDVGPL 
301:	VKLTLNVCDI TLRAFITRSS LVELGIEEGK EVYASFKASA IHVF