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3.A.1.6.5
Tungsten (KM=20pM)/molybdate (KM=10nM) porter (Bevers et al., 2006)

Accession Number:Q8U4K4
Protein Name:WtpB
Length:249
Molecular Weight:27336.00
Species:Pyrococcus furiosus [2261]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Molybdate, Tungstate

Cross database links:

HEGENOM: HBG685300
RefSeq: NP_577810.1   
Entrez Gene ID: 1467910   
Pfam: PF00528   
KEGG: pfu:PF0081   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Tungsten transport protein A (WtpA) in Pyrococcus furiosus: the first member of a new class of tungstate and molybdate transporters.”  Bevers L.E.et.al.   16952940

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDRRDYLAYA FAGLGAFLVA FIGLPLFMIF IKQAYDLEAL QRTLVDPLVI ESIRNSLFTA 
61:	TVSTLLGILF GVPLGYVLAR KEFKGKNFVQ ALIDTPIVIP HSVVGIMLLV TFSDAILDNY 
121:	KGIVAVMLFV SSPFIVNSAR DGFLSVDEKL EYVARTLGAS GLRTFFSVTL PNAIHSIASG 
181:	AIMAWARAIS EVGAILIVAY YPKTAQVLIM EYFNNYGLRA SRPIAVILVT ISLAVFIFLR 
241:	WLVGRGRNA