TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.6.5
Tungsten (KM=20pM)/molybdate (KM=10nM) porter (Bevers et al., 2006)

Accession Number:Q8U4K5
Protein Name:WtpA
Length:345
Molecular Weight:38801.00
Species:Pyrococcus furiosus [2261]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Molybdate, Tungstate

Cross database links:

HEGENOM: HBG457285
RefSeq: NP_577809.1   
Entrez Gene ID: 1467909   
Pfam: PF01547   
KEGG: pfu:PF0080   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0046872 F:metal ion binding
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Tungsten transport protein A (WtpA) in Pyrococcus furiosus: the first member of a new class of tungstate and molybdate transporters.”  Bevers L.E.et.al.   16952940
Structure:
3CG1     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MREGGVMKKR LLALIVAFAV LTAGCLGSES KEVTLIVFHA GSLSVPFQEV EKEFSEYAER 
61:	NLGIKVSFQD EASGSVMAVR KVTDLGRKAD VIGVADYTLI PQLLIPNYTD FYVLFATNEI 
121:	VIAFTDKSRY VEEMKSNPDK WYEILAREDV RFGFSDPNQD PCGYRSLMVI KLADLYYGKE 
181:	IFKELIEENT NIYSNGTQIY APKEITVNPG KIVIRPKETD LLGLVESGSI DYIFIYKSVA 
241:	KQHNLSYITL PSEINLGDFS KEKFYGQISI TLGSTGKTIK AKPIVYGVTV LKDAPNREVA 
301:	IEFLRYLLSE NGKRIFEKNH QDFLEPPIAF GNVPEELKPL VSIEK