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3.A.1.5.24
The antimicrobial peptide (protamine, melittin, polymyxin B, human defensin (HBD)-1 and HBD-2 exporter, YejABEF (Eswarappa et al., 2008). Prefers N-formyl methionine peptides, such as Microcin C (of prokaryotic origin) to non formylated peptides (of eukaryotic origin) (Novikova et al., 2007).

Accession Number:Q8ZNJ8
Protein Name:YejF
Length:529
Molecular Weight:58515.00
Species:Salmonella typhimurium [90371]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_461163.1   
Entrez Gene ID: 1253741   
Pfam: PF00005    PF08352   
BioCyc: STYP99287:STM2219-MONOMER   
KEGG: stm:STM2219   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0015833 P:peptide transport

References (1)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTSPLLAIEN LSVGFRQQQH VRPVVNAISL QVNAGETLAL VGESGSGKSV TALSILRLLP 
61:	TPPAVYLSGD IRFHGESLLH ASEQTLRGVR GNKIAMIFQE PMVSLNPLHT LEKQLYEVLS 
121:	LHRGMSREAA RAEMIGCLDR VGIRQASQRL RDYPHQLSGG ERQRVMIAMA LLTRPELLIA 
181:	DEPTTALDVS VQAQILSLLR ELQRELNMGL LFITHNLSIV KKLADSVAVM QHGKCVENQR 
241:	ADTLLSAPTH PYTQKLLNSE PTGDPVPLPA GQAPLLEVDK LRVAFPIRKG ILKRVVDHNV 
301:	VVNNISFTLH PGETLGLVGE SGSGKSTTGL ALLRLIRSEG RIVFDGQSLD TLNRRQLLPV 
361:	RHRIQVVFQD PNSSLNPRLN VLQIIEEGLR VHQPTLSGAQ REQQVKAVMM EVGLDPETRH 
421:	RYPAEFSGGQ RQRIAVARAL ILKPSLIILD EPTSSLDKTV QAQILALLKS LQQKHRLAYI 
481:	FISHDLHVVR ALCHQVIVLR QGEVVEQGQC ERVFTAPQQA YTRQLLALS