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3.A.1.5.24
The antimicrobial peptide (protamine, melittin, polymyxin B, human defensin (HBD)-1 and HBD-2 exporter, YejABEF (Eswarappa et al., 2008). Prefers N-formyl methionine peptides, such as Microcin C (of prokaryotic origin) to non formylated peptides (of eukaryotic origin) (Novikova et al., 2007).

Accession Number:Q8ZNJ9
Protein Name:YejE
Length:341
Molecular Weight:38155.00
Species:Salmonella typhimurium [90371]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides

Cross database links:

HEGENOM: HBG729429
RefSeq: NP_461162.1   
Entrez Gene ID: 1253740   
Pfam: PF00528   
BioCyc: STYP99287:STM2218-MONOMER   
KEGG: stm:STM2218   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MPRLSPVNQA RWARFRHNRR GYWSLWIFLV VFSLSLCAEL IANDKPLLVR YEGQWYFPLV 
61:	KNYSERDFGG PLATTADYQD PWLQRQLENR GWVLWAPVRF SANTINFATT QPFPSPPSAK 
121:	NWLGTDANGG DVFARILYGT RISILFGLML TICSSVMGVL AGALQGYYGG KVDLWGQRLI 
181:	EVWSGMPTLF LIILLSSVVQ PNFWWLLAIT VLFGWMSLVG VVRAEFLRTR NFDYIRAAQA 
241:	LGVSDRDIIL RHMLPNAMVA TLTFLPFILC SSITTLTSLD FLGFGLPLGS PSLGELLLQG 
301:	KNNLQAPWLG IAAFLSVAIL LSLLIFIGEA VRDAFDPAKA V