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3.A.1.5.24
The antimicrobial peptide (protamine, melittin, polymyxin B, human defensin (HBD)-1 and HBD-2 exporter, YejABEF (Eswarappa et al., 2008). Prefers N-formyl methionine peptides, such as Microcin C (of prokaryotic origin) to non formylated peptides (of eukaryotic origin) (Novikova et al., 2007).

Accession Number:Q8ZNK0
Protein Name:YejA
Length:601
Molecular Weight:69179.00
Species:Salmonella typhimurium [90371]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate peptides

Cross database links:

HEGENOM: HBG289570
RefSeq: NP_461160.1   
Entrez Gene ID: 1253738   
Pfam: PF00496   
BioCyc: STYP99287:STM2216-MONOMER   
KEGG: stm:STM2216   

Gene Ontology

GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MIARVMLLLV ALVSAGAQAQ EIKESYAFAV LGEPKYAFNF EHFDYVNPAA PKGGQMTLSA 
61:	IGTFDNFNRY SLRGNPGVRT EALYDTLFTT SDDEPGSYYP LIADHARYAA DYSWVEISIN 
121:	PRARFHDGTP ITARDVAFTF HKFMTEGVPQ FRLVYKGTTV KAIAPLTVRI ELAKPGKEDM 
181:	LSLFSLPIMP EKFWKNHKLS DPLSTPPLAS GPYRITQWKM GQYIVYSRVK NYWAANLPVN 
241:	RGRFNLDTIR YDYYLDDNVA FEAFKAGAFD LRLENDAKNW ATRYIGKNFD NHYIIKEEQK 
301:	NESAQDTRWL AFNIQRPVFK DRRVREAVTL AFDFEWMNKA LFYNAWSRTN SYFQNTEYAA 
361:	RNYPDADELV LLAPMKKDLP PEVFTQIYQP PVSNGDGYDR ENLLKADALL TQAGWVINGQ 
421:	QRVNSVTGKP LTFELLLPAS SNSQWVLPFQ HNLQRLGITM TIRQVDNSQL TNRMRSRDYD 
481:	MMPRLWRAMP WPSSDLQISW ASEYIDSSYN APGVQSPVVD KLIAQIIAAQ GDKAKLVPLG 
541:	RALDRVLTWN YYMLPMWYMA QDRLARWDKF SHPAIRPVYT IGLDTWWYDV NKAAKLPAAR 
601:	R