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3.A.1.6.2
Tungstate porter. (TupA, the receptor, exhibits an extremely high affinity for tungstate (Kd <1 nM) and discriminates between tungstate and molybdate (Andreesen and Makdessi, 2007))

Accession Number:Q93KD6
Protein Name:TupA
Length:286
Molecular Weight:30875.00
Species:Eubacterium acidaminophilum [1731]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Tungstate

Cross database links:

Pfam: PF01547   

Gene Ontology

GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Tungstate uptake by a highly specific ABC transporter in Eubacterium acidaminophilum.”  Makdessi K.et.al.   11292832

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKRLLSIITA VMMLALALTG CAAKQSPEGE VEKTQAKGSI ILATTTSTSD SGLLDYLLPE 
61:	FTKDTGIEAK VVAVGTGQAL QMGKDGEADV LLVHSKAAEE EFVAAGDGLE RKDVMYNDFI 
121:	LVGPANDPLK LKQELPNDIV GALKKISEQK FKFISRGDDS GTHKKELALW TEVGITPEGD 
181:	YYVSAGRGMG DVLKMADEMQ AYTIADRGTY LSMKADLGLD IIVEKDTNLF NQYGVIPVNP 
241:	DKNENINAEG AKAFEEWILS EKAQSLIGEY GKEKYGAPLF TPNAAK