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3.A.1.14.19
Heme uptake porter, HugBCD (Villarreal et al., 2008); also called HmuTUV.

Accession Number:Q93SS2
Protein Name:HugC
Length:353
Molecular Weight:36810.00
Species:Plesiomonas shigelloides [703]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Heme

Cross database links:

Pfam: PF01032   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Characterization of the Plesiomonas shigelloides genes encoding the heme iron utilization system.”  Henderson D.P.et.al.   11292789

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLRLKLSLLG SSGLLLLSFM LLLSIATGPV RLPLSESLQA LLSLPSHAND LSTQQLIIQT 
61:	IRLPRTLLCI SVGGILALAG AVLQGLFRNP LADPGIIGVS GGAALGAGLS IVLLPAGVSL 
121:	AGLSIAGFSL GWLSLGYTAL CAFLCGMLTT LLVYRIGRTP FGTSVNMMLL AGVAIGAIAF 
181:	SGLGLLSYLA DDQQLRDLSL WQMGSLAGAR WDTLLLSSLT LLVLLVGFYR QAPALNALLL 
241:	GESEARHLGV NVERLKRRLI IGCAVGIGVS VSVSGMIGFI GLIVPHLVRM LCGPDYRNLL 
301:	PLSALCGAIL LLLADLLARQ LAAPAEIPVG IITALLGAPF FIWLLIQQKR SAA