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3.A.1.14.19
Heme uptake porter, HugBCD (Villarreal et al., 2008); also called HmuTUV.

Accession Number:Q93SS3
Protein Name:HugB
Length:315
Molecular Weight:32832.00
Species:Plesiomonas shigelloides [703]
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Heme

Cross database links:

Pfam: PF01497   

Gene Ontology

GO:0005381 F:iron ion transmembrane transporter activity
GO:0006827 P:high-affinity iron ion transport

References (1)

[1] “Characterization of the Plesiomonas shigelloides genes encoding the heme iron utilization system.”  Henderson D.P.et.al.   11292789

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKQMRLSRYA LLACLSLPTV TLHAAPTDSA ATNTHPVAAS AIPPTGPQST PKIAPTRVIS 
61:	AGSNVTEIIV ALGAGDVLVG VDSSSRLPAD SKAATLGYIR QLPAEGMLAL RPDYVIGSDE 
121:	MAPASALTAL QQAKIPLTVL PSDTTPEALK AQVTQIAALL HKEAAGQTLQ TKIDQQLEQL 
181:	AQTRAQLQGK QHGKPLKAVY LLLHDGRPPM IAGGNTPADT LLTLAGAVNP AAAVRNYQTV 
241:	SAESLLAMQP DLIVVSERNW TGDADSLLAK QPLLQNTPAG RNKAVLPING KALIGGIGLS 
301:	TLNEAQRLAN HLNQQ