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3.A.1.135.1
The heterodimeric multidrug exporter, YdaG/YbdA  (Both proteins are ABC half transporters; only the heterodimer is active; ethidium, daunomycin and BCECF-AM are substrates; Lubelski et al., 2004) These proteins have been renamed LmrC and LmrD (Lubelski et al., 2006)

Accession Number:Q9CIP5
Protein Name:YdbA; aka ABC transporter ATP binding and permease protein
Length:664
Molecular Weight:74026.00
Species:Lactococcus lactis (subsp. lactis) (Streptococcus lactis) [1360]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ethidium, Daunomycin, 2,7-bis(carboxyethyl)-5(6)-carboxyfluorescein-acetoxymethylester

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_266467.1   
Entrez Gene ID: 1113921   
Pfam: PF00664    PF00005   
BioCyc: LLAC272623:L110899-MONOMER   
KEGG: lla:L110899   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (1)

[1] “The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.”  Bolotin A.et.al.   11337471

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MENTKSTRKM SDTTRAIRFF YLYLKRYKLQ FAVIMIFIIL ATWLQVVSPS LLGDAITNLT 
61:	KYVTDFFTHQ HAGQSQDALQ QIAQQLSQQM HQTVDWHNVP EVVKSLPQAA QDQITANLPK 
121:	GTTLETLKTV ATSHAASTST FMKGMWQLLA VYVATGVSML IYTLLFSRIV AHSTNRMRKG 
181:	LFGKLERLTI SYFDRHQDGD ILARFTSDLD NIQNTLNQAL VSVISNAAVF VGVIIQIFNK 
241:	DVTFAWLTVA ASPVAILSAV IIIRQSKKAT DKQQEEVSQL NAYMDEKISG QKAIIVEGLQ 
301:	EDSINGFLEH NENVKKRTFA AQAWSGMIFP LMNGFQLLSI AIVIFGGTAY VLNDDSMSIA 
361:	TGLGLLVAFV QYVQSYYNPI MQISSNFGQL QLAITGATRL NVMFDEPEEV RPENGKKFDT 
421:	IKDGIQIENL DFEYLPGKPV LKKVNIDVKK GQMVALVGPT GSGKTTVMNL MNRFYDVNGG 
481:	AIKFDGTDIR EFDLDSLRSN VGIVLQESVL FDGTIADNIK FGKPNATQEE IETVAKTTHI 
541:	HDFIDSLPDK YETHVSDDES VFSVGQKQQI SIARTILTNP ELLILDEATS NVDTVTEQQI 
601:	QWAMEAAIAG RTSFVIAHRL KTILNADKIV VLKDGEVIEE GNHHELVAQG GFYSELYHNQ 
661:	FVFE