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3.A.1.135.1
The heterodimeric multidrug exporter, YdaG/YbdA  (Both proteins are ABC half transporters; only the heterodimer is active; ethidium, daunomycin and BCECF-AM are substrates; Lubelski et al., 2004) These proteins have been renamed LmrC and LmrD (Lubelski et al., 2006)

Accession Number:Q9CIP6
Protein Name:YdaG; aka ABC transporter ATP binding and permease protein
Length:573
Molecular Weight:63172.00
Species:Lactococcus lactis (subsp. lactis) (Streptococcus lactis) [1360]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Mitochondrion1
Substrate ethidium, Daunomycin, 2,7-bis(carboxyethyl)-5(6)-carboxyfluorescein-acetoxymethylester

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_266466.1   
Entrez Gene ID: 1113920   
Pfam: PF00664    PF00005   
BioCyc: LLAC272623:L109162-MONOMER   
KEGG: lla:L109162   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (1)

[1] “The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.”  Bolotin A.et.al.   11337471

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKHKWVALFS IVSTFIYAGV QLYQPQIMKR IMTVMSSTTY SRHQMADKVS GYGVELLVVA 
61:	GIGIIFAIFS TLSAARIAQE IGADVREATY KKINTFSYEN IEKFNAGNLV VRMTNDVTQV 
121:	QNLMMMVFQI LMRIPVLLIG AVVLSITTLP RLWWITVLLI VLIVLVTAVL MGRMGPHFMA 
181:	FQKLMDRINA IAKQNLRGSR VVKSFVQEKN QIKDFDETSD ELYDHNWAVG KLFSAMIPLF 
241:	TVIAQGVIWL AIYFVSTFVT ESTTVAQDSI GGIATFMTYM GMIMFAIIMG GMISMFASRG 
301:	MVSIGRINEV LNTDPAMKFD ENAKDEVLSG SVKFDHVSFS YPNDEEPTLK DISFEVEPGQ 
361:	MVGIVGATGA GKSTLAQLIP RLFDPTEGTV SVGGKDLKTV SRGTLKKNIS IVLQKAILFS 
421:	GTIAGNIKQG KADATDEEMT RAARIAQAAE FITTKDGQYD SEVEERGNNF SGGQKQRLSI 
481:	TRGVVKNPNV LILDDSTSAL DAKSEKLVQE ALNKDLKDTT TIIIAQKISS VVHADNILVL 
541:	DQGKLVGQGT HQELVAENKI YQEIYDTQKA QED