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3.A.1.17.6
Putative hydroxymethylpyrimidine transport system, ThiXYZ (Rodionov et al., 2002). Regulated by TPP (thiamin) riboswitch. Potentially takes up a pyrimidine moiety of thiamin. ThiY is homologous to the yeast THI5 HMP-P synthase (P43534) (Bale et al., 2010).

Accession Number:Q9CLG9
Protein Name:Putative uncharacterized protein
Length:254
Molecular Weight:28298.00
Species:pasteurella multocida [747]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Hydroxymethylpyrimidine

Cross database links:

HEGENOM: HBG754934
RefSeq: NP_246202.1   
Entrez Gene ID: 1244612   
Pfam: PF00528   
KEGG: pmu:PM1265   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Complete genomic sequence of Pasteurella multocida Pm70.”  May B.J.et.al.   11248100

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRGNMKIKPL IHVVLLSLML LALWQSAVFF FDIPRYMLPP PNDVLAQLHN RYDLLWQHSQ 
61:	ITLLEIGLGL FLGVSLGLIS ALLLSASDYL SKLLLPLLVI SQAIPVFAIA PLLVLWFGYG 
121:	LASKIVMTIL IIYFPVTAAC YDGLRNTSMQ WLELAKTMQV SASAMLFKVR LPAALPSFAS 
181:	GLRIAVSVAP IGAIVGEWVG SSQGLGYLML HANARMQVDL MFSALLILMV ISLVLYFSVD 
241:	YFLRKWLPWV QYIK