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2.A.6.2.42
SmeDEF MDR efflux pump. Mediates resistance to a wide range of drugs including ethidium bromide and norfloxacin (Alonso and Martínez, 2000). Regulated by SmeT and activated by insertion of the transposon, IS1246 (Gould and Avison, 2006).

Accession Number:Q9F239
Protein Name:Outer membrane protein
Length:466
Molecular Weight:50021.00
Species:Stenotrophomonas maltophilia (Pseudomonas maltophilia) [40324]
Number of TMSs:1
Substrate ethidium bromide, norfloxacin

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEVIPMKSAS LFLSIAATLA LAGCSTLAPK NTAVAPAIPA QWPAEAAQGE VADVAAVGWR 
61:	DFFTDARLQQ VIEQSLQNNR DLRVAVLNVE RARGQYRVQR ADRVPGVAVT GQMDRRGTDA 
121:	GVTEQFSAGV GVAEFELDLF GRVRNLSEAA LQQYFAVAAN RRNAQLSLVA ETATAWLTYG 
181:	ADAQRLKIAD ATLKTYEDSL RLAEARHERG GSSALELTQT RTLVETARTD AARLRGQLAQ 
241:	DRNALALLAG GQLDPALLPD SIEPQLLALA PPPAGLPSDV LLQRPDIMAA EHQLLAANAN 
301:	IGAARAAFFP SISLTGSIGS GSSELSNLFD SGTRVWSFLP KITLPIFQGG KLRANLAIAN 
361:	ADRDIALAQY EKSIQVGFRE TADALALNVS LDEQVSSQQR LVEAAEQANR LSQARYDAGL 
421:	DSFVTLLDAR RTAYNAQQTQ LQAQLAQQAN RITLYKVLGG GWHERG