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2.A.6.2.42
SmeDEF MDR efflux pump. Mediates resistance to a wide range of drugs including ethidium bromide and norfloxacin (Alonso and Martínez, 2000). Regulated by SmeT and activated by insertion of the transposon, IS1246 (Gould and Avison, 2006).

Accession Number:Q9F240
Protein Name:Putative RND protein
Length:1040
Molecular Weight:111297.00
Species:Stenotrophomonas maltophilia (Pseudomonas maltophilia) [40324]
Number of TMSs:12
Substrate ethidium bromide, norfloxacin

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MARFFIDRPI FAWVIAIIIM LAGGLALFKL PVSMYPNVAP PAVEISATYP GASAKVVEDS 
61:	VTQIIEQNMK GLDGLIYFSS NSSSNGQATI TLTFESGTNP DIAQVQVQNK LQLAMPLLPQ 
121:	EVQRQGINVA KSSSGFLNAI AFVSENGSMD ANDIADYVGS NVVDRLSRVP GVGNIQVFGG 
181:	KYAMRIWLDP NKLHTYGLSV PEVTAAIKAQ NAQVAIGQLG GAPSVKGQQL NATINAQSRL 
241:	QTPEQFRNII VRGAQDGAEL RLGDVARVEL GAESYDFVTR YNGQPASGLA VTLATGANAL 
301:	DTAAGVDAAL EDMKGFFPAG LKAEIPYDTT PFVRVSIKGV VQTLIEAIVL VFVVMYLFLQ 
361:	NFRATLIPTI AVPVVLLGTF GVLAMLGFSV NMLTMFAMVL AIGLLVDDAI VVVENVERIM 
421:	SEEGLSPLEA TRKSMGQITG ALVGIGLVLS AVFVPMAFMS GSTGVIYRQF SATIVSAMAL 
481:	SVLVAIVLTP ALCATMLKPL KKGEHHVAHR GLAGRFFNGF NRGFDRTSES YQRGVRGIIH 
541:	RPWRFMGIVA ALFVLMGVLF VRLPSSFLPN EDQGVLMALV QAPVGATQER TLESIAALEN 
601:	HFLQNEKDAV DSVFSVQGFS FAGMGQNAGM AFVKLKDWSE RDADNGVMPI TGRAMAALGQ 
661:	IKDAFIFAFP PPAIPELGTA SGYTFFLKDN SGQGHEALVA ARNQLLGLAA GSKKLANVRP 
721:	NGQEDTPQFR IDIDAAKATS LGLSIDQING TLAAAWGSSY IDDFVDRGRV KRVFVQADQA 
781:	FRMVPEDFDL WSVKNDKGEM VPFSAFATKH WDYGSPRLER YNGVSAMEIQ GEPAPGVASG 
841:	DAMAEIEQLA KQLPAGFGIE WTAMSYQERQ AGSQTPLLYT LSLMIVFLCL AAMYESWSVP 
901:	TAVLLAAPLG ILGAVLANTF KGLERDIYFQ VAMLTTVGLT SKNAILIVEF AKENLEKGAS 
961:	LIESIMHAVR DRLRPIVMTS LAFGMGVVPL AISTGAGSGA KQAIGTGVLG GMIVGTVLGV 
1021:	FFVPLFFVVV QRVFKRRSTT