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3.A.1.12.12
The CbcWV/CbcX (choline)/CaiX (carnitine)/BetX (betaine) transporter with 3 binding receptors for distinct quaternary ammonium compounds. Only the ligand-bound receptor binds to the transporter with high affinity (Chen et al., 2010; Thomas et al., 2010).

Accession Number:Q9HTI8
Protein Name:Probable ATP-binding component of ABC transporter
Length:392
Molecular Weight:43722.00
Species:Pseudomonas aeruginosa [287]
Substrate Glycine betaine, Carnitine, Choline

Cross database links:

HEGENOM: HBG758042
Entrez Gene ID: 880284   
Pfam: PF00005   
KEGG: pae:PA5376   

Gene Ontology

GO:0016020 C:membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (1)

[1] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTAIRFDHVD VIFGTHTKEA LKLLDQGLGR AEILKRTGQV LGVEDACLDV NRGEICVLMG 
61:	LSGSGKSSLL RCINGLNKVS RGKLLIEHEG SQVDIANCSP ATLKAMRTKR IAMVFQKFAL 
121:	MPWLTVAENV GFGLEMQGRP AAERKKLIDE KLELVGLSQW RDKRPDSLSG GMQQRVGLAR 
181:	ALAMDGDILL MDEPFSALDP LIRQQLQDEL LVLQRQLHKT IVFVSHDLDE ALKIGTRIAI 
241:	MKDGRIIQHG KPEEIVLSPA DDYVRTFVAH TNPLNVLCGQ SLMRGLDQCI RQNDEICFDQ 
301:	GRDCWIGLSE GDVLKGARQG SNVIDLQRWR QGDPVEKLRR EPTLVDVSIR MRDALQIRYQ 
361:	TGHKLVLQEQ DRVVGVLGDS ELYHALLGKN LG