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3.A.1.5.14
Probable cellobiose porter. Induced by barley, glucomannan (Conners et al., 2005)

Accession Number:Q9X0V0
Protein Name:TM1223
Length:557
Molecular Weight:64078.00
Species:Thermotoga maritima [2336]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cellobiose

Cross database links:

HEGENOM: HBG617256
RefSeq: NP_229028.1   
Entrez Gene ID: 898261   
Pfam: PF00496   
Drugbank: Drugbank Link   
BioCyc: TMAR243274:TM_1223-MONOMER   
KEGG: tma:TM1223   

Gene Ontology

GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima.”  Nelson K.E.et.al.   10360571
Structure:
1VR5   4PFT   4PFY     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKRFLVVLVL VLALVSVFGQ TFERNKTLYW GGALWSPPSN WNPFTPWNAV AGTIGLVYEP 
61:	LFLYDPLNDK FEPWLAEKGE WVSNNEYVLT LRKGLRWQDG VPLTADDVVF TFEIAKKYTG 
121:	ISYSPVWNWL GRIERVDERT LKFVFSDPRY QEWKQMLINT PIVPKHIWEN KTEEEVLQAA 
181:	NENPVGSGPY YVESWADDRC VFKKNGNWWG IRELGYDPKP ERIVELRVLS NNVAVGMLMK 
241:	GELDWSNFFL PGVPVLKKAY GIVTWYENAP YMLPANTAGI YINVNKYPLS IPEFRRAMAY 
301:	AINPEKIVTR AYENMVTAAN PAGILPLPGY MKYYPKEVVD KYGFKYDPEM AKKILDELGF 
361:	KDVNKDGFRE DPNGKPFKLT IECPYGWTDW MVSIQSIAED LVKVGINVEP KYPDYSKYAD 
421:	DLYGGKFDLI LNNFTTGVSA TIWSYFNGVF YPDAVESEYS YSGNFGKYAN PEVETLLDEL 
481:	NRSNDDAKIK EVVAKLSEIL LKDLPFIPLW YNGAWFQASE AVWTNWPTEK NPYAVPIGWN 
541:	GWWQLTGIKT LFGIEAK