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3.A.1.5.15
Probable mannose/mannoside porter. Induced by beta-mannan (Conners et al., 2005). Regulated by mannose-responsive regulator manR (Kazanov et al., 2012).

Accession Number:Q9X268
Protein Name:TM1746
Length:642
Molecular Weight:73659.00
Species:Thermotoga maritima [2336]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Mannosides, Mannose

Cross database links:

HEGENOM: HBG465619
RefSeq: NP_229544.1   
Entrez Gene ID: 897084   
Pfam: PF00496   
BioCyc: TMAR243274:TM_1746-MONOMER   
KEGG: tma:TM1746   

Gene Ontology

GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima.”  Nelson K.E.et.al.   10360571

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRKFVVGFLM VLVAAFYFSE VEVQLPWFGV TNFDPYYWQA QHILAQGTIF EGLFGYVPDP 
61:	KSLGGVKVVP AVCESYTVSE DGLTYTFYLR KDKRWSNGDP VTAYDFEFAW KRAASPETPT 
121:	LPLWASPVQY IKNVYDCKSG AKPLDELGVK ALDDYTLQVT LSRPMPSFIN MLVLGGAMPL 
181:	HRKTVQEHPE DWWKPEYFVG NGPYVIESFT PNYEIVLVRN KYYVGDFPGN VDRIVLKAGG 
241:	LGLQQYLAGE IDAVFITAVG DYVFALKNKQ LSKELHEESG VQWVGYEITR SLSPVFDDIR 
301:	IRKALAMAID KKVLTDIVLG GMAIPTHAYC SPDSEIAEAV KGIPYDPEQA KKLLAEAGYP 
361:	NGKGFPKVKF YITGASDPVA EALVDQWKKV LGITFEIENI ESGQFSTLQW SDFVPWAEPG 
421:	VCTIGGPVNW QDSGSLMQTA DHTFWFYDYP AEVRQKLYEL REKRESVLRE EGGKTEEEWK 
481:	EILNRAQELW EKWQEVVNSE PDEFLKKYFL LPAPGELTFI EQINKLYEEW KKATTDEQKI 
541:	QLWRLAMRAI YNQEYSLVEY TGMNPTNREA RRLWARILYS PYDKAVEYAK KLQQLCVDLA 
601:	YEVPLYVQKV VYLAKPYLKG IVPYKFSWGP TFFLFKYLTV EK