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3.A.1.5.15
Probable mannose/mannoside porter. Induced by beta-mannan (Conners et al., 2005). Regulated by mannose-responsive regulator manR (Kazanov et al., 2012).

Accession Number:Q9X269
Protein Name:TM1747
Length:341
Molecular Weight:37977.00
Species:Thermotoga maritima [2336]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Mannosides, Mannose

Cross database links:

HEGENOM: HBG724229
RefSeq: NP_229545.1   
Entrez Gene ID: 897865   
Pfam: PF00528   
BioCyc: TMAR243274:TM_1747-MONOMER   
KEGG: tma:TM1747   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima.”  Nelson K.E.et.al.   10360571

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNSEPWDFPG LLLNMSNGVV DMRFLKFLLK RLLTIAISMV VVIVITYVLM WLAPGNFFEL 
61:	QRVRDAIARV TTPDDPAYQA TLKGFEERYG LNNPLWKQIL MYLKGAVVFK FGPSFSDPAR 
121:	NIEDLIKEKF PITFTLALSS ILFALVVGVP LGILAALKKN TWIDYTAMTV SVIGVAIPSY 
181:	VVAVFLILIF SIYLGWLPTS GWEGIRTKIL PTIALALGPL ASVARFTRVS LLDTLNQDFI 
241:	RTAYAKGGDD RTVIMKHALR PSMIPLVTIV GPQMAYLMVG TVWVENIFRI PGLGQLFANA 
301:	AVTRDYPLLV TSTFILALTV MIMNLIVDVL YAILDPRIKL D