TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.5.15
Probable mannose/mannoside porter. Induced by beta-mannan (Conners et al., 2005). Regulated by mannose-responsive regulator manR (Kazanov et al., 2012).

Accession Number:Q9X270
Protein Name:TM1748
Length:289
Molecular Weight:31656.00
Species:Thermotoga maritima [2336]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Mannosides, Mannose

Cross database links:

HEGENOM: HBG729429
RefSeq: NP_229546.1   
Entrez Gene ID: 897182   
Pfam: PF00528   
BioCyc: TMAR243274:TM_1748-MONOMER   
KEGG: tma:TM1748   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima.”  Nelson K.E.et.al.   10360571

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLRKNKTESI GYWKAFWLRF KKNKMAVIGG VFVLILIALA ILAPYIAPYP YDEPHYIRAF 
61:	EGPSKDFIFG TDALGRDLFS RILYSLRNAC IIGFGSQFVV LIIGGILGAV AGFKGGWIDK 
121:	FIMSIVDIMF AFPTFLFNVI LVTALGRGLF TIFLAIGLTG WAGMARLVRG QVLYLKNSEF 
181:	VEAAKAAGAS TFYIIRKHIL PNMIGPILVN LAFGVPGAMM TESGLAVIGM GVRPPMPSWG 
241:	NLIGEGIGMM MAFPHLLIFP AVTFAFTLIS FTFLADGLRD AFNPRSEIS