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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007).

Accession Number:Q9XC06
Protein Name:TadA
Length:426
Molecular Weight:47140.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate proteins

Cross database links:

Pfam: PF00437   

Gene Ontology

GO:0005622 C:intracellular
GO:0005524 F:ATP binding
GO:0006810 P:transport

References (3)

[1] “Nonspecific adherence by Actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea.”  Kachlany S.C.et.al.   11029439
[2] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[3] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLTKQQKILL RSEVLSNLDI EKIDELQSER SSLVNELVQI VNRVANKSGA YLTSADTLVM 
61:	AEIVADEIEG YGPLRDLMAD DTINDILVNG PNDIWVERAG ILEKTDKEFV SNEQLTDIAK 
121:	RLVARVGRRI DDGSPLVDSR LPDGSRLNVV IAPIALDGTS ISIRKFSKNK KTLQELVNFG 
181:	SMTREMANFL IIAARSRVNI IVSGGTGSGK TTLLNALSNY ISHTERVITL EDTAELRLEQ 
241:	PHVVRLETRL AGVEHTGEVT MQDLVINALR MRPERIIVGE CRGGEAFQML QAMNTGHDGS 
301:	MSTLHANSPR DATSRLESMV MMSNASLPLE AIRRNISSAV NIIVQASRLN DGSRKIMNIT 
361:	EVMGMENGQI VLQDMFSYKA SKYRDKEGKI LGEFINHGLL TRSIVFQNAQ VFNLSAELQS 
421:	IFGETE