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1.A.1.11.18
The nicotinic acid adenine dinucleotide phosphate (NAADP)- dependent two pore Ca2+- channel, TPC3 (Brailoiu et al., 2010).

Accession Number:C4IXV8
Protein Name:Two pore channel 3
Length:768
Molecular Weight:88011.00
Species:Bos taurus (Bovine) [9913]
Number of TMSs:12
Substrate Ca2+

Cross database links:

Entrez Gene ID: 100297753   
Pfam: PF00520   
KEGG: bta:100297753   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005216 F:ion channel activity

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPGNSRAAGT HHSRPSSSEE PPDLEDQELL LAAAYVSDAQ YNRNVPFETS PQAIRLYHFY 
61:	NHWTMRAATY FFIWVNLALA LFEEPAVFPL PFLVTSIAEV LCLTAFFGRL VHFAKVTPQK 
121:	VFWKDTKNIC VMVTIVLTLI DLVIYGSLEA VNIRGVRWSR ALRPVFLINF PESRQIRRTF 
181:	RSIRNTLPDI LYVFLLFLFS MMIFSLMALK LFGDRDLRTV EGSPYFTNIL DIAFELYVLV 
241:	TTANSPDVMM PAYELNWWYS LYFITYIIIN TYIFMSVFLA VIYNNYRKHL KNEIHTLAYL 
301:	KHHKMTEAFN ILKVKVGTEF VVKEARWRRL VKVVAPDVSS SHLELLLRIS DEGQKGHVDK 
361:	VNFLRLADLL NIRVVAINIK KHPLETWMPR VYQSSTSLLV QKMVQHRIFV WVYDVIILIN 
421:	AIFIALDEKD SLISYAEWLF LSLYIIEILL KLYTYEPSAY FGRKQFWNWF DTLIIIAALL 
481:	ATVANTTIQA RKYNSQQVLD IVLILRILRL LRVIVSIQRF RVIVTTLINI GPTMLTFGGL 
541:	VLVVYYAFAI IGMEVFHGKI HFLDPGSGSP DALVCGNPAL KDSAFAQGRY CKNNFNDLAS 
601:	SLILLTELTV VNQWHILADG FALVTHQAAK LYFIGFHVVV VILIVNIFIA FILEAFFVAY 
661:	SLEKSEVETA IEKKIQELGV GVQEEEVQDG GLIDNMDAKD SGFSPDEGDN KKKDLKGLYF 
721:	RIASKKYKTV DTLLQQMFES EIAPEGKDPS LKEILSFSPK KVNFDNSA