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1.A.1.11.28
Voltage-dependent L-type calcium channel subunit α, VDCC, CCA-1 or CaACNa1S, of 1873 aas and 24 TMSs. Ca2+ channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.  They are regulated by dystrophin-1 (Zhan et al. 2014).

Accession Number:Q7YZR6
Protein Name:Calcium Channel, Alpha subunit
Length:1844
Molecular Weight:210763.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:16
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ca2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLRQPVPELR SFQSLSKYAG GPRSVLGRRT SAITVNRRQS QSTRRHEDVE ALGSIEGSKE 
61:	TLQLSEHGRL ASSSEASPSR WEGRQIEWGN EEQIEEESEL PYPGFAEPAL RCFYQARPPR 
121:	KWALQMVMSP WFDRITMAVI MINCVTLGMY RPCEDGPDCD TYRCQILDII DNCIFVYFAF 
181:	EMVIKIMALG FYGPAAYMSD TWNRLDFFIV MAGIAEFVLH EYLGGNINLT AIRTVRVLRP 
241:	LRAVNRIPSM RILVNLLLDT LPMLGNVLLL CFFVFFIFGI VGVQLWAGLL RNRCVINLPK 
301:	TISENQSALF NNVKLTRFYI PEDTSLEYIC SQPDANGLHT CSNLPPYTVD GVKCNLTLDE 
361:	YDKVTNDSCI NWNIYYNECQ VMQRNPFQGS VSFDNIGFAW VAIFLVISLE GWTDIMYYVQ 
421:	DAHSFWNWIY FVLLIVIGAF FMINLCLVVI ATQFAETKRR ETERMLQERK MLLNRDSISC 
481:	TGSEIGGASS KEEGDTVYAA FVRFIGHTFR RTKRAAKKKY TAYMEERAER KSSERQQRRK 
541:	SKLDDMATLS RIEEKAEDEE DETTITRENG DDQIEQNGDG VRIKRVKIEE EPKIKIGNGN 
601:	SNGPHYKHSS SDEESDEDGE EDQVYDGEEA KKKSTPSKLW WFREKIQKFV ICDHFTRGIL 
661:	VAILVNTLSM GVEYHQQPEI LTVILEYSNL FFTALFALEM LLKIIASGLF GYLADGFNLF 
721:	DGGIVALSVL ELFQEGKGGL SVLRTFRLLR ILKLVRFMPA LRYQLVVMLR TMDNVTVFFG 
781:	LLVLFIFIFS TLGMVLFGCK FCNHPDTGLQ CTSAQVISSI CECDRMNFDN FLFATVTVFQ 
841:	ILTQEDWNMV LFNGMAQTNP WAALYFVALM TFGNYVLFNL LVAILVEGFQ ESKEEEKRQL 
901:	EEDARKQAVE EEDERKRELE LIIAKTTSPA FNNGVAPAEC TCQRPSSPEE SPSPRLLSAN 
961:	YHPSPERKHS ANLDAIIDKR LVLRNSAPFD RSPVSEGRDD SRLNRHASLV LPVANGVPYR 
1021:	RQRVHSWSGL CHHFNPNCPV HGRRALIETY AREKFLEASQ ELKQALAEEE KRNEAKQNTF 
1081:	VRKLLKKTCL HNRTEFSLFL MGPKNPLRIK CLQTTQKKWF DYTVLFFIGI NCITLAMERP 
1141:	SIPPDSFERQ FLHISGYIFT VIFTGEMMMK VIANGCFIGQ AAYFKDGWNI LDGILVVISL 
1201:	INIAFELLAT GDSPKIFGVI RVLRLLRALR PLRVINRAPG VKLVVMTLIS SLKPIGNIVL 
1261:	ICCTFFIIFG ILGVQLFKGM MYHCIGPEVG NVTTKADCIE DYRNKWVNHR YNFDNLGQAL 
1321:	MSLFVLSSKD GWVSIMYQGI DAVGVDVQPI ENYNEWRMIY FISFLLLVGF FVLNMFVGVV 
1381:	VENFHKCKEA LEKEMREKEK EKRLKRKLKR QKFEESMAGK RKKMERNYPY YHDYGHTRLF 
1441:	LHGIVTSKYF DLAIAAVIGI NVISMAMEFY MMPMGLKYVL KALNYFFTAV FTLEAAMKLI 
1501:	ALGFKRFFIE KWNRLDMFIV ILSIAGIIFE EFEALELPIN PTIIRVMRVL RIARVLKLLK 
1561:	MAKGIRSLLD TVGEALPQVG NLGSLFFLLF FIFAALGVEL FGKLECSEDH PCDGLGEHAH 
1621:	FKNFGMAFLT LFRIATGDNW NGIMKDALRD DCDSSDHCET NCCVDPILAP CFFVIFVLIS 
1681:	QFVLVNVVVA VLMKHLEESN KRDAEGPAEP TGENIENEIT KSDDDEIVEE HEPLAIEHVK 
1741:	EGELDEEEET EEGPTTQIPD GHGGIKRLSM QVLEQELIEV ERHLEERYRR ASECLGGELQ 
1801:	PLNPGEIEDL DDPEFRPRSR SHRPRARTNS ALSNKSRGSH KSAL