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1.A.1.11.35
Calcium channel of 2725 aas and 24 TMSs.  T. cruzi calcium channels are inhibited by fendiline and bepridil (Reimão et al. 2011).

Accession Number:Q4DZ99
Protein Name:Calcium channel protein, putative
Length:2725
Molecular Weight:307293.00
Species:Trypanosoma cruzi (strain CL Brener) [353153]
Number of TMSs:22
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSGVPPAYPV DSNIGVPNAH TQQRLPASGS QSNTSSRVII GGVAPPTSTG RPHLPLPLPP 
61:	VKGAASQPPL TGTGSVPAPG HPPMGRLTPL QHRTLDGTEA QPGARPSPPP RLPMNSSTTQ 
121:	PTEASGAAEN GDGQSSAAGG LPTFHATINP LSPISQQEQL RQQRQHTPSR KTTDRAGTSS 
181:	ARSRKTMTPA SQQGTRPQSA ISGEETVEVL CPLPTQTRPV ERFFVEFNPG AIVGNGRDDN 
241:	AMYEEALLFD RLAEYTEDDS FFSSGSSVLE EDPRRLQKDI FRERAVRSVY DTLNLRALTG 
301:	GRTPQELEDK NRENAGWMYQ VHRRAIALHH SSFFVFPAGM KARVVTYNVL HHWLMELMIL 
361:	LIILGYSIFT ASWSRYGAPE FEKPDFMVFA DFLYTILYGI EIIARLFASG CILHSRAYFR 
421:	SPWHWLDTAV FVLMIMNCTQ WRDLWNFTAF RLIRIIKACT YLPLPIRMKI IAKSVLRSTC 
481:	KLFQTSIILV YALFFFALLG LQLFRGVLHY RCVNSLTGAA TSQLCRPEAT GHYWFYWGHV 
541:	CDPGYICISD GFPNPNYDFR SFDDVGHALL STFQIMTFQG WTSLLQETND AVTTLAFLYY 
601:	FFTILLCAWL IPGLFIGVFI EKIEKTSRLF EQKQLELFDA MLLEQRQRLT EAIKLRDFVE 
661:	RDECGRLRGH LAEAAPEDTS YPTLRVNSAS SNGKFPESGS FNSRNSERNT SVVTGSSGAA 
721:	KKRTKWTDEQ RVQLHLSLTR QRDIAEQGER RRRVIFKVDK KETDHTNGNF EMSSVSTNTT 
781:	NNMGGGDFAL GGRVGTVQHH PLTYTIGAAH GTRLPLAVRL ENEQERLQFL KYYQQAEEAD 
841:	DTTLQGGLTR GSRGVDGSTN NNMNSSHLSH SHPMRRGVGH GDEMGSDIIT IRESAGVIPN 
901:	RRSATTRGNT SGASTSLRTS TAAAAALNGS AGGVAQSQEI LIHDPEGGDF RYAKTFGQSW 
961:	GIIRNILHMF TEGCPRILTQ YLWEHRRMQT RFGLLPLNYV NKYEEAALRK LRQKRARRGK 
1021:	LILKNNRIED DGTDDYSEPE EPANEDQEYL GKLSPIRMAK NIVENAPVTL FSGIMLFLVF 
1081:	ANGVFNASRH YGQPVYWEDG LFIAGVCFTS LFMLELIIRF IVLGPGPFVC DFINVICVIV 
1141:	TVIGFFELGF GHSNTITVLN WVRFLRLFRI APFAPMRRVT RVFLLGFQDI VYALILFSVY 
1201:	MFMWILTGMS FFGGRFGRLT TQNDDYATIG FFDTFSHATF AVAQAFSYVR DEWLYLSWDG 
1261:	MRVRGGYTII YFLAVVFVAF IFRYLFIAVF AWAWQQQEER EDYVLHTTSK GGHQNRGGPR 
1321:	LHWFDFTVWR SFKHIHGGFE RRDVAPDEVF HLNQDMRRQL RIAEAKERFT RESMTRRGFS 
1381:	ADPQTIFSDS FSTNGNVASY GMPSSAPPLM LAPQFVNVGG QLQRQMSMPS TFDEPPPHPA 
1441:	QAPISRFQAE NAQLRFARRY SAVPATPYRG VAEELNGAHF LPVTSTPSDQ ALHNSNGSVA 
1501:	DTAAETEGLS HQIGGRASGL YGVHGSSNLP NEHHSSVTGY FTTLGYDKSG EKKNGEAMEN 
1561:	YQQSSENEEN GDPENSVVDG GGGGGGSGGV VYEHVLLPGP RLRYKHIMVG RHRRVFERCL 
1621:	DCNVHKQIPL RAPPNVQQRT ADELHAEHCH MAAVRSSRQL VLNTIIGYVR LQKELGGPPT 
1681:	REAVETVLGQ AWSCGMLLFE SIEYLSCADI ELREYRTWDR TLEALQLQQW LIGLHLGEEQ 
1741:	VGRATLAYIL AHQKTQERVA THSSFHRSWR DRSFFIFSPS HPARRFLTAI VESKWFEWFI 
1801:	LAVIFAASIC LCFYSPEDED RTSKKYLALH ILDDIFAIIF AVEMVLKWIS MGVVLDCHVA 
1861:	YFWHRWNTFD CFITIISLIA IAPKYSHFRF LKVMRCFRIL GPMRYCRFNK ELSKLALTMW 
1921:	DSVPTLVNVL LLFLLNYIVW SILALRLFMG LTHSCTSHAF SNKTSCEEAG AMWLGPQRNF 
1981:	DNFYESLLTM FEVSTGSRWL DVIYTGVDGW SMEFEPIYNR HPSKGLFFVA YYYVSHFVLF 
2041:	SLFVASLIYC YLLAKNAAEG VTDITFEHQL WLRMQRMILR LRPRVELVPL GNCLSRFLHR 
2101:	IVIHPAFELV MAGILLCNMI TMSLYWYGNS SRQEKALDIL EHLWVAFFTL EILMKLTAHG 
2161:	LRAFSRYSFC FQVFVTSLSY LQIGLNTTVG NHVPFNVNTL RLLHLGRMLK LVDFLVPVRH 
2221:	HLHLLHEALL LSASSLVNVT LILALAVFVF AVLGMHFIGP VVPVAGQYID DTYNNFRTFP 
2281:	NALMMIFRLA TLEDWVSMLR SSMSDGNNCP ISDCKTTNWA PVFYVPIVIC FALMIVNLYL 
2341:	AVVVDHYVTV VRMKASVARI NDLRRFRDLW SARDPNATLL LRTRKLPELL EALRPPLGLS 
2401:	SRKNRAELLR LLREYDIPDH GGKVHYYEVL LPLARRVLAM AFSEDEIDDG VKFEAVWRLS 
2461:	ESSLRALPTV LVHHSSATAA QHFAASYVQA AYRRDKACRK LHEMRANCWR EARRICDELG 
2521:	LPYKDYGFGD VSLEDEDPRN EAARRGLLNE STNEEKKQKN AADVTAAAAF AAAGRSESMT 
2581:	TDSNESSGKP APAARLPGLY QPAIDEKEKR FGPDVPHAVR RHETRSDKLR RKEEERQQQQ 
2641:	QQDPMDRQPS VPPAPRSTAQ RNQSIDYQPP LGTDPSEWLQ NEMGRRMSGA GAGTLSSANH 
2701:	TGAGGGASPT KATAPPSSEG LDGNV