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1.A.1.13.3
Divalent cation (Ca2+, Mg2+, Mn2+, Ni2+)-activated K+ channel, TuoK (contains a RCK domain) (Parfenova et al., 2007)

Accession Number:Q979Z2
Protein Name:Potassium channel protein aka TuoK
Length:348
Molecular Weight:38605.00
Species:Thermoplasma volcanium [273116]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Mn2+, Mg2+, Ca2+, Ni2+

Cross database links:

RefSeq: NP_111507.1   
Entrez Gene ID: 1441128   
Pfam: PF07885    PF02254   
KEGG: tvo:TVN0988   

Gene Ontology

GO:0005488 F:binding
GO:0003824 F:catalytic activity
GO:0008324 F:cation transmembrane transporter activity
GO:0005216 F:ion channel activity
GO:0008152 P:metabolic process
GO:0006813 P:potassium ion transport

References (1)

[1] “Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium.”  Kawashima T.et.al.   11121031

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRPFRTLVKV LQKIESSPLT KVFMAFIIVV LIGSYLEFLT QRNVKYSEIK NYFTAIWFTM 
61:	ETVTTVGYGD VVPVSNLGRV VAMLIMVSGI GLLGTLTATI SAYLFQIRIE RRGKLEKRLK 
121:	NHTIICNWNA YTRNIIEGNR DEEAAPIVIL SENTDNSEKY QNVFFVKGDC TSEDDLKNAA 
181:	IEDAARVVIM SDIENNAIPE DLLDAKTLLS IFTVRKLNNA VEIIAEVRDE KNKKHAVSAG 
241:	ATEVLSVGEL SSRLISRSIS NPGLTDFILK SLSETEDFKI FSIEACGILP GMTVKDAASN 
301:	LAEVCVIISV ISKGKIEYPP DRSYKIGAGD YVVFLAKNKK EVEEAIKG