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1.A.1.13.4
The Biofilm-inducing putative K+ channel, BikC or YugO (Prindle et al. 2015). BikC has an N-terminal 2 TMS + P-loop channel domain and a C-terminal NADB_Rossman superfamily domain (TrkA domain). YugO is in a two cistronic operon where Mistic (MstX; 9.A.66; Debnath et al., 2011; Roosild et al., 2005) is encoded by the gene that precedes yugO. Both play a role in biofilm formation, probably by functioning together (Lundberg et al. 2013; Marino et al. 2015). These K+ channels in bacterial biofilms provide an active, long-range electrical signalling for cellular communities (Prindle et al. 2015).  Metabolic co-dependency gives rise to collective electrical oscillations in biofilms (Liu et al. 2015). This oscillatory electrical signalling, due to periodic release of K+, giving rise to K+ gradients, increasing as swimming cells approach the biofilm that generates the gradiens, allows cells of the same and different speices to find and then incorporate themselves into existing biofilms (Humphries et al. 2017).

Accession Number:Q795M8
Protein Name:Putative potassium channel protein yugO
Length:328
Molecular Weight:36579.00
Species:Bacillus subtilis [1423]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

HEGENOM: HBG313806
Entrez Gene ID: 938842   
Pfam: PF07885    PF02254   
KEGG: bsu:BSU31322   

Gene Ontology

GO:0008076 C:voltage-gated potassium channel complex
GO:0005488 F:binding
GO:0005249 F:voltage-gated potassium channel activity

References (2)

[1] “Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai).”  Oudega B.et.al.   9274030
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKSNRIFISW LRWPLFIRIG VIILCLILLF GQIIYILEPK QFTSVFEGIW WAVVTVSTVG 
61:	YGDYVPHTPL GQAAGILLIL SGASFVTAYF ATLSAAAFSR QHRYIEGKVA YKGRDHIILI 
121:	GWNEKTNRLL KDLQLAAPSK TVVLIDESLT EGPLIENVHF IRGHAADDGT LKRANITEAE 
181:	SVMITADQYK SETDADMLSV LTLLSVKGLN PLAYCIVEIL TDRFVTNAER AGANQIIGTS 
241:	EFISRAMLQH YQVKLRPSKQ QNGIKLTLDQ HVELLAVPDE LKGAAYKTCV LYFLDHNTTI 
301:	IGIQKKEGPM LSPPLTYKVL ETDQFLAI