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1.A.1.2.20
Shaker K+ channel, Shk-1, Shk1, Kv1 of 536 aas and 6 TMSs.  Mediates the voltage-dependent potassium ion permeability of excitable membranes. Has an important role in repolarization and in regulating the pattern of action potential firing. Isoform a expresses currents in a more depolarized voltage range than isoform d (Liu et al. 2011).

Accession Number:Q8I4B0
Protein Name:Potassium voltage-gated channel protein shk-1
Length:536
Molecular Weight:61234.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate K+

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRFGGQRRCI ESSDDNDSID SMSIQQKNKE KEEWKWAQSL ARRLEQVLNV HPEKYQNGCS 
61:	SQRPSRQPSP VEQLAPIRSH SADFGRAAEM ASGNSEEGKG MLLRNGDDRI RLPSPQRGTP 
121:	DTSSTQGHPY TDQIVTINVS GMRFQTFEST LSRYPNSLLG DRNKRQHFFV SDTNEFFFDR 
181:	HRTTSSSFTF EIRNYLFESI LYIYQSGGRV KRPEIVPIDI FLKEMRFFQM GDDLLEEFWI 
241:	AEGYEKPKEV MMPNNKTQRK IWELMEYPDS SLSARIIAFI SIAVIALSII SFCWETVPSD 
301:	IEEKPINNSA TAELLDEMDE KHYSPFFWIE LMCILWFTIE LILRFISCPC KVTFATSVLN 
361:	IIDFVAIAPF FVNFFFADTS KSNSSMSFAV LRVLRLVRVF RVFKLSRHSV GLQILGKTFR 
421:	SSVQEFCLLI FFMAIALVLF ASGMYFAEQG EPNSKFTSIP ASFWFVLVTM TTVGYGDLVP 
481:	LSPFGKVVGG MCAMIGVLTL ALPVPIIVAN FKHFYRQENR LASMKSKGDD ADDDIA