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1.A.1.2.3
Voltage-sensitive fast transient outward current K+ channel in neurons and muscle of flies and worms (Fawcett et al., 2006)

Accession Number:P17971
Protein Name:Shal2 aka Shal aka CG9262
Length:490
Molecular Weight:55919.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

eggNOG: inNOG09065
DIP: DIP-19398N
RefSeq: NP_524159.1   
Entrez Gene ID: 40129   
Pfam: PF00520    PF02214    PF11601   
BioCyc: DMEL-XXX-02:DMEL-XXX-02-017372-MONOMER   

Gene Ontology

GO:0008076 C:voltage-gated potassium channel complex
GO:0005250 F:A-type (transient outward) potassium channe...
GO:0005515 F:protein binding
GO:0006813 P:potassium ion transport
GO:0055085 P:transmembrane transport

References (4)

[1] “K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.”  Wei A.G.et.al.   2333511
[2] “Shal, Shab, and Shaw: three genes encoding potassium channels in Drosophila.”  Butler A.et.al.   2336395
[3] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132
[4] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MASVAAWLPF ARAAAIGWVP IATHPLPPPP MPKDRRKTDD EKLLINVSGR RFETWRNTLE 
61:	KYPDTLLGSN EREFFYDEDC KEYFFDRDPD IFRHILNYYR TGKLHYPKHE CLTSYDEELA 
121:	FFGIMPDVIG DCCYEDYRDR KRENAERLMD DKLSENGDQN LQQLTNMRQK MWRAFENPHT 
181:	STSALVFYYV TGFFIAVSVM ANVVETVPCG HRPGRAGTLP CGERYKIVFF CLDTACVMIF 
241:	TAEYLLRLFA APDRCKFVRS VMSIIDVVAI MPYYIGLGIT DNDDVSGAFV TLRVFRVFRI 
301:	FKFSRHSQGL RILGYTLKSC ASELGFLVFS LAMAIIIFAT VMFYAEKNVN GTNFTSIPAA 
361:	FWYTIVTMTT LGYGDMVPET IAGKIVGGVC SLSGVLVIAL PVPVIVSNFS RIYHQNQRAD 
421:	KRKAQRKARL ARIRIAKASS GAAFVSKKKA AEARWAAQES GIELDDNYRD EDIFELQHHH 
481:	LLRCLEKTTM