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1.A.1.3.7
Slo2.2 sodium-activated potassium channel subfamily T member 1 of 1217 aas and 6 putative N-terminal TMSs plus a P-loop.  Cryo electron microscopic structures of the chicken orthologue at 4.5 Å resolution has been solved, revealing a large cytoplasmic gating ring in which resides the Na+-binding site and a transmembrane domain that closely resembles voltage-gated K+ channels (Hite et al. 2015).

Accession Number:C9J9Y7
Protein Name:Potassium channel subfamily T member 1
Length:1217
Molecular Weight:138011.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:8
Substrate K+

Cross database links:

Structure:
5a6e     

External Searches:

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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSDLDSEVLP LPPRYRFRDL LLGDPSFQND DRLPVEDFSL DSSLSQVQVE FYVNENTFKE 
61:	RLKLFFIKNQ RSSLRIRLFN FSLKLLTCLL YIVRVLLDDP ALGIGCWGCP KQNYSFNDSS 
121:	SEINWAPILW VERKMTLWAI QVIVAIISFL ETMLLIYLSY KGNIWEQIFR VSFVLEMINT 
181:	LPFIITIFWP PLRNLFIPVF LNCWLAKHAL ENMINDFHRA ILRTQSAMFN QVLILFCTLL 
241:	CLVFTGTCGI QHLERAGENL SLLTSFYFCI VTFSTVGYGD VTPKIWPSQL LVVIMICVAL 
301:	VVLPLQFEEL VYLWMERQKS GGNYSRHRAQ TEKHVVLCVS SLKIDLLMDF LNEFYAHPRL 
361:	QDYYVVILCP TEMDVQVRRV LQIPLWSQRV IYLQGSALKD QDLMRAKMDN GEACFILSSR 
421:	NEVDRTAADH QTILRAWAVK DFAPNCPLYV QILKPENKFH VKFADHVVCE EECKYAMLAL 
481:	NCICPATSTL ITLLVHTSRG QEGQESPEQW QRMYGRCSGN EVYHIRMGDS KFFREYEGKS 
541:	FTYAAFHAHK KYGVCLIGLK REDNKSILLN PGPRHILAAS DTCFYINITK EENSAFIFKQ 
601:	EEKRKKRAFS GQGLHEGPAR LPVHSIIASM GTVAMDLQGT EHRPTQSGGG GGGSKLALPT 
661:	ENGSGSRRPS IAPVLELADS SALLPCDLLS DQSEDEVTPS DDEGLSVVEY VKGYPPNSPY 
721:	IGSSPTLCHL LPVKAPFCCL RLDKGCKHNS YEDAKAYGFK NKLIIVSAET AGNGLYNFIV 
781:	PLRAYYRSRK ELNPIVLLLD NKPDHHFLEA ICCFPMVYYM EGSVDNLDSL LQCGIIYADN 
841:	LVVVDKESTM SAEEDYMADA KTIVNVQTMF RLFPSLSITT ELTHPSNMRF MQFRAKDSYS 
901:	LALSKLEKRE RENGSNLAFM FRLPFAAGRV FSISMLDTLL YQSFVKDYMI TITRLLLGLD 
961:	TTPGSGYLCA MKITEGDLWI RTYGRLFQKL CSSSAEIPIG IYRTESHVFS TSEPHDLRAQ 
1021:	SQISVNVEDC EDTREVKGPW GSRAGTGGSS QGRHTGGGDP AEHPLLRRKS LQWARRLSRK 
1081:	APKQAGRAAA AEWISQQRLS LYRRSERQEL SELVKNRMKH LGLPTTGYED VANLTASDVM 
1141:	NRVNLGYLQD EMNDHQNTLS YVLINPPPDT RLEPSDIVYL IRSDPLAHVA SSSQSRKSSC 
1201:	SHKLSSCNPE TRDETQL