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1.A.1.5.17
Cyclic nucleotide-gated K+channel of 430 aas.  Activated by cAMP, not by cGMP.  Highly specific for K+ over Na+.  Has a C-terminal cAMP-binding domain linked to the 6 TMS channel domain (Brams et al. 2014).

Accession Number:G0GA88
Protein Name:Putative transcriptional regulator, Crp/Fnr family
Length:430
Molecular Weight:48269.00
Species:Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203) [869211]
Number of TMSs:3
Substrate K+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKSSGVSNPT YTLVWKVWIL AVTLYYAIRI PLTLVFPSLF SPLLPLDILA SLALIADIPL 
61:	DLAFESRRTS GRKPTLLAPS RLPDLLAALP LDLLVFALHL PSPLSLLSLV RLLKLISVQR 
121:	SATRILSYRI NPALLRLLSL VGFILLAAHG IACGWMSLQP PSENPAGTRY LSAFYWTITT 
181:	LTTIGYGDIT PSTPTQTVYT IVIELLGAAM YGLVIGNIAS LVSKLDAAKL LHRERVERVT 
241:	AFLSYKRISP ELQRRIIEYF DYLWETRRGY EEREVLKELP HPLRLAVAME IHGDVIEKVP 
301:	LFKGAGEEFI RDIILHLEPV IYGPGEYIIR AGEMGSDVYF INRGSVEVLS ADEKTRYAIL 
361:	SEGQFFGEMA LILRAPRTAT VRARAFCDLY RLDKETFDRI LSRYPEIAAQ IQELAVRRKE 
421:	ELEGGTSRRG