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1.A.17.1.28
Anoctamin1, Ano1, TMEM16A of 979 aas and 10 TMSs. It is probably an anion (Cl-) cannel. Fertilization activates TMEM16A channels in X. laevis eggs and induces the earliest known event triggered by fertilization: the fast block to polyspermy (Wozniak et al. 2018).

Accession Number:B5SVV6
Protein Name:Anoctamin
Length:979
Molecular Weight:113226.00
Species:Xenopus laevis (African clawed frog) [8355]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIMAAKLDER VHEAPIPMNN INMDLLSQVG LTNLLNSLGA DRETGCKHGI FFKDGQRKVD 
61:	YILAFTYKKS GSRTPNKKNH HNNSVHNLHS PKDDHHLPGG GGDLEAMEAE PKMDYHEDDK 
121:	RFRREEYEGN LIETGLELER DEETKLHGVG FVKIHAPWNV LCREAEFMKL KMPTKKVYQI 
181:	NQTQGLMQKL SSFIHKISEP IQPKVAGLRP QTVKHLSYPF SREKQHLFDM SDKESFFDSK 
241:	TRSSIVYEIL KRTTCTKAKY SMGITSLLAN GVYSAAYPLH DGDYDSEAEA NDRKLLSDEW 
301:	ASYSAFYKYQ PIDLVRKYFG EKIGLYFAWL GVYTQMLIPA SVVGIIVFLY GCATVDENIP 
361:	SMEMCDTRYN ITMCPLCDRT CNYWKMSSAC GTARASHLFD NPATVFFSVF MALWAASFME 
421:	HWKRRQMRLN YRWDLTGFEE EEGMVKDHPR AEYEAKVLQK SLKKEYRSKE KQQHVPEDNP 
481:	NKWKQRVKTA MAGVKLTEKE KLTWRDRFPA YLTNVVGIIF MIGVTFAIVF GVIMYRISTA 
541:	AALAMSSNPN TRANVRVTVT ATAVIINLVV ILILDEVYGA IARWLTQIEV PKTDKTFEER 
601:	LIFKAFLLKF VNAYTPIFYV AFFKGRIVGR PGDYYYIFQS FRMEECAPGG CLMELCIQLS 
661:	IIMLGKQLIQ NNLFEIGIPK MKKLIRYLKS KRQSYKDHEE HLKKKQRYEE DYDLEPFAGL 
721:	TPEYMEMIIQ FGFVTLFVAS FPLAPLFALL NNIIEIRLDA KKFITELRRP VAVRAKDIGI 
781:	WYNIIRGVGK LAVIINAFVI SFTSDFIPRL VYLYMYSPDG TMHGFVNHTL SYFNVSDFKL 
841:	GTEPSQPVDL GYKVEMCRYK DYREAPWSLN KYDINKDYWA VLAARLAFVI VFQNLVMFMS 
901:	DFVDWIIPDI PKDISEQIHR EKVLMVEVFL KEEQGKLQML ETWKEHERKK GENCNSQSPG 
961:	LSRSQRGSSS SMYSHRVDV