TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.A.29.1.1









Putative amide transporter (AmiS) (Wilson et al., 1995).

Bacteria
Proteobacteria
AmiS of Pseudomonas aeruginosa
*1.A.29.1.2









Putative amide transporter (AmiS)
Bacteria
Actinobacteria
AmiS of Rhodococcus erythropolis
*1.A.29.1.3









Proton-gated urea transport channel (UreI) (pH-sensitive). Allows the transmembrane flow of urea, hydroxyurea and (at a low rate) water. KB for urea is ~150mM (Sachs et al., 2006; Scott et al., 2010). Transport kinetics and selectivity have been defined (Gray et al., 2011).  The 3-d structure reveals a hexameric protein with a channel included within the twisted 6 TMS bundle of each protomer.  It displays a two helix hairpin structure repeated three times around the central axis of the channel (Strugatsky et al. 2012). 

Bacteria
Proteobacteria
UreI of Helicobacter pylori
*1.A.29.1.4









Urea transporter channel (UreI) (pH-insensitive)
Bacteria
Firmicutes
UreI of Streptococcus salivarius
*1.A.29.1.5









Urea transporter channel (UreI) (pH-sensitive)
Bacteria
Proteobacteria
UreI of Helicobacter hepaticus (AAK69200)
*1.A.29.1.6









The hexameric ring urea/acetamide/small amide channel, UreI (7 TMSs) (Huysmans et al., 2012).

Bacteria
Firmicutes
UreI of Bacillus cereus (Q814I5)