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1.A.3.1.10
Ryanodine receptor, RyR, of 5139 aas and 6 TMSs. Sensitive to the diamide insecticides, chlorantraniliprole and flubendiamide. It has the conserved C-terminal domain with the consensus calcium-biding EF-hands (calcium-binding motif), the six transmembrane domains, as well as mannosyltransferase, IP3R and RyR (pfam02815) (MIR) domains (Wu et al. 2018). Probably transports monovalent cations and Ca2+.

Accession Number:AXA98483.1
Protein Name:AXA98483.1 Ryanodine receptor [Sesamia inferens]
Length:5140
Molecular Weight:
Species:Sesamia inferens [492764]
Number of TMSs:4
Substrate

Cross database links:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAESEGGASE QDDVSFLRTE DMVCLSCTAT GERVCLAAEG FGNRHCFPEN IADKNIPPDL 
61:	SQCVFVIEQA LSVRALQELV TAAGSETGKG TGSGHRTLLY GNAILLRHLN SDMYLACLST 
121:	SSSQDKLAFD VGLQEHSQGE ACWWTLHPAS KQRSEGEKVR VGDDLILVSV ATERYLHTTK 
181:	ENEVSIVNAS FHVTHWSVQP YGTGISRMKY VGYVFGGDVL RFFHGGDECL TIPSTWTKDG 
241:	GQNIVVYEGG SVMSRARSLW RLELARTKWA GGSINWYHPM RIRHITTGRY LGVNDQNELY 
301:	LVSREEATTA SCAFCLRQEK DDQKQVLEDK DLEVIGAPII KYGDSTVIVQ HSETGLWLSY 
361:	KSYETKKKGV GKVEEKQAIL HEEGKMDDGL DFSRSQEEES RTARVIRKCS SLFTKFINGL 
421:	ETLQENRRHS MFFASVNLGE MVMCLEDLIN YFAQPDDDME HEEKQNRFRA LRNRQDLFQE 
481:	EGILNLILEA IDKINVITSQ GFLAGFLAGD ESGQSWEMIS GYLYQLLAAI IKGNHTNCAQ 
541:	FANSNRLNWL FSRLGSQASG EGTGMLDVLH CVLIDSPEAL NMMRDEHIKV IISLLEKHGR 
601:	DPKVLDVLCS LCVGNGVAVR SSQNNICDYL LPGKNLLLQT ALVDHVSSVR PNIFVGRVEG 
661:	SAVYRKWYFE VTMDHIEKTT HMMPHLRIGW ANTTGYVPYP GGGEKWGGNG VGDDLYSYGF 
721:	DGAYLWSGGR KTMVNRTHQE EPYIRKGDVI GCALDLTVPI INFMFNGMRV TGSFTNFNLE 
781:	GMFFPVISCS SKLSCRFLLG GEHGRLRYAA PEGYSPLVES LLPQQILSLE PCFYFGNLSK 
841:	RALAGPPLVQ DDTAFVPTPV DTIQITLPSY VEQIRDKLAE NIHEMWAINK IEAGWMYGDQ 
901:	REDLHKIHPC LVPFERLPPA EKRYDIQLAV QTLKTILALG YYISLDKPPA RIRNVRLPNE 
961:	PFMQSNGYEP APLDLSAVTL TPKMDELVDQ LAENTHNLWA RERIQQGWTY GLNEDPDMHR 
1021:	SPHLVPYPKV DDAIKKANRD TASETVRTLL VYGYMLDPPT GEQHEALLLE ASKQKQADFR 
1081:	TYRAEKNYAV GSGKWYFEFE ILTAGPMRVG WAHADMAPGM MLGQDENSWA FDGYNEEKVY 
1141:	SGSTESFGKQ WAVGDVVGVF LDLIDKTISF SLNGELLMDA LGGETTFADV QGDNFVPACT 
1201:	LGVGQKARLT YGQDVNTLKY FTTCGLQEGY EPFCVNMKRD VTHWYTKDQP IFENTDEMTD 
1261:	TGIDVTRIPA GSDTPPCLKI SHNTFETMEK ANWEFLRLSL PVICHLEFID ESEKARRWIE 
1321:	IKERQQILMK EAVEAQMPAH IDQIMRSGFT MNDIKGMHYE DNQEEMPTSS KAKRLPSRPP 
1381:	RKGSVTRGVS IQNYNNLQTG PQVNGMHRST SEAEMAKYEL GAQNLAPDDK KDKRGRSPFK 
1441:	FFRSKRGESN DRGKSRKSKT PDPFSDTEVS PERGPRRPNP QIKVSQANQK YNGMNARPSR 
1501:	ANLYGSQAGL NMATPTQDRK QMTTSTLAQS ATETVGNEIF DAECLKLINE YFYGVRIYPG 
1561:	QDPTHVYIGW VTTQYHLHSK DFNQSKVTKS SVIITDDYDR IIENVNRQSC YMVRADELYN 
1621:	EVMAEATAKG ASQGMFIGCS VDTSTGTVSF TCEGKDTSIK FKMEPETKLF PAIFVEATSK 
1681:	EILQIELGRS TTSLPLSAAV LPTSDKHVIP QFPPRLKVQC LSPHQWARVP NQSLQVHALK 
1741:	LSDIRGWSML CEDAVSMLAL HIPEEDRCID ILELIETDKL LSFHSHTLTL YAALCYQSNY 
1801:	RAAHALCTHV DQKQLLYAIQ SQYMSGPLRQ GFYDLPIALH LESHATTMEA CKNEFVIPLG 
1861:	PELKSLYEDP DMGHSLRSLQ TESVCPQMKM TDIAESITEI SNLYSPYFPL EVVREFVMQA 
1921:	LAEAVETNQV HNRDPVGGSN ENLFLPLIKL VDRLLLVGMM RDEDVEKLLI MINPETWDPS 
1981:	FDREGKDEHR KGLLHMKMAE GAKLQMCYLL QHLNDIQLRH RVEAIIAFAH DFVGDLQTDQ 
2041:	LRRYTEIKQS DLPSAVAAKK TREYRCPPRE QMNAILSFKH LEESEEKDNC PCGEELIARM 
2101:	NDFHESLMAH VSLHALQEPD GSENQEPEAK PGAFGQLYNI INTVKDMEEE AKAIEEPIRK 
2161:	TPEEKFRKVL IQTIVSWAEE SQIETPKLVR EMFSLLVRQY DAVGELIRAL EKTYVINAKT 
2221:	KLDVAEMWVG LSQIRALLPV QMSQEEEELM RKRLWKLVNN HTFFQHPDLI RVLRVHENVM 
2281:	AVMMNTLGRR AQAQSDAQPA SPPVTEDKQE KDTSHEMVVA CCRFLCYFCR TGRQNQKAMF 
2341:	DHFDFLLENS NILLSRPSLR GSTPLDVAYS SLMENTELAL ALREHYLEKI AVYLSRCGLQ 
2401:	SNSELIEKGY PDLGWDPVEG ERYLDFLRFC VWVNGESVEE NANLVIRLLI RRPECLGPAL 
2461:	RGEGEGLLKA IVDANKMSER IADRRKLREI EQEGDVTFTH PLPESDEDED YIDTGAAILN 
2521:	FYCTLVDLLG RCAPDAGVIA LGKNESLRAR AILRSLVPLE DLQGVLSLRF TLNNPAAGEE 
2581:	RPKSDMPSDL IPGHKQSVGL FLERVYGIET QELFYKLLEE AFLPDLRAAT MLDRNDGCES 
2641:	DMALSMNRYI GNSILPLLIK HAYFYNEAEN YASLLDATLH TVYRLSKNRM LTKGQREAVS 
2701:	DFLVALTSAM QPSMLLKLLR KLTVDVSKLS EYTTVALRLL TLHYERCAKY YGSTGAGQGV 
2761:	FGASSDEEKC LTMMLFSNIF DSLSKMDYEP ELLGKALPCL IAIGCALPPD YSLSKNYDDE 
2821:	FYGKEQVTGG LDNPQYDPQP INTSSVALNN DLNTIVQKFS EHYHDAWASR KIENGWVYAE 
2881:	SWSDSQKSHP RLKPYNMLND YEKERYKEPV RESLKALLAI GWSVEHSEVD IPSTNRSSMR 
2941:	RQSKSGGRPP DIVTDSATPF NYNPHPVDMT NLTLSREMQN MAERLADNAH DIWAKKKKEE 
3001:	LVTNGGGIHP QLVPYDLLTD KEKKKDRERS QEFLKYLQYQ GYKLHRPSKA PQSDTEQTTT 
3061:	GVAIELRFAY SLLEKLIQYI DRATINMKLL KPSTTFSRRS SFKTSTRDIK FFSKVVLPLM 
3121:	EKYFSTHRNY FIAVATATNN IGAASLKEKE MVAALFCKLA SLLRSRLAAF RPDVRITVRC 
3181:	LQVLVKGIDA KSLVKNCPEF IRTSMLTFFN NVADDVGHTI NNLQEGKYAH LRGTHLKTST 
3241:	SLGYINGVLL PILTAKFDHL ANCEYGSDLL LDEIQVASYK MLGSLYALGT DATLTHDRKY 
3301:	LKTEIERHKP ALGSCLGAFS STFPVAFLEP HLNKHNQFSL LNRIADHSLE AQDIMQKMEQ 
3361:	CMPTLETILG EVDQFVESDK TYNEAPHIID VVLPLLCSYL PFWWAQGPDN VTPTGGNHVT 
3421:	MVTAEHMNQL LKNVLKLIKK NIGNENAPWM TRIATYTQQI IINSSEELLR DSFLPLAERV 
3481:	RKRTDNMFHK EESLRGFIKS STDDTSQVES QIQEDWQLLV RDIYSFYPLL IKYVDLQRNH 
3541:	WLRNNVPEAE ELYNHVAEIF NIWSKSQYFL KEEQNFISAN EIDNMVLIMP TATRRLTAVT 
3601:	DGTPQAGGKK KKKHRDKKRD KDKEVQASLM VACLKRLLPV GLNLFAGREQ ELVQHCKDRF 
3661:	LKVGTLKKMS EQDVAEFAKT QLTLPDKIDP ADEMSWQHYL YSKLGSKSKS NITVETAENK 
3721:	AKIIDDTVER IVAMSKVLFG LHMIDHPQQM SKNVYRSVVS IQRKRAVIAC FRQTSLHSLP 
3781:	RHRACNIFAR TYYELWLEEE NKGQEVMIED LTQSFEDAEL KKSDVVEEGE KPDPLTQLVT 
3841:	TFCRGAMTER SGALQEDPLY MSYAHIIAKS CGEEEEEGGG EEEEGGGGEP EAEEEGRASI 
3901:	HEQEMEKQKL LFHQARLADR GVAEMVLLHI SASKGLPSEM VMKTLQLGIS ILRGGNIDIQ 
3961:	MGMLNHLKDK KDVGFFTSIA GLMNSCSVLD LDAFERDTKA EGLGVGLEGA AGEKNMHDAE 
4021:	FTCALFRFIQ LTCEGHNLDW QNYLRTQAGN TTTVNVVICT VDYLLRLQES IMDFYWHYSS 
4081:	KELIDPAGKA NFFKAIGVAS QVFNTLTEVI QGPCTQNQQA LAHSRLWDAV GGFLFLFSHM 
4141:	QDKLSKHSSQ VDLLKELLNL QKDMITMMLS MLEGNVVNGT IGKQMVDTLV ESASNVELIL 
4201:	KYFDMFLKLK DLTSSASFQE IDANSDGWVL PKDFKEKMEQ QKSYAPEEIE FLLACCETNH 
4261:	DGKLDYVGFC DRFHEPAKEI GFNLAVLLTN LSEHMPNEPR LARFLETAGS VLNYFEPFLG 
4321:	RIEIMGGSKR IERVYFEIKE SDIEQWEKPQ IKESKRAFFY SIVTEGGDKE KLEAFVNFCE 
4381:	DAIFEMTHAS GLMAASEESV GGTKNREASY MYMGDDDDER AGKDPFRRGL QSVKDGFATA 
4441:	FSSLSPSNIK QKIADMQQMP PAELAVGFFK MFFYLFYYLG YGVLVVVRYI LGVLLGLMRG 
4501:	PQTDEPPPEP TEEEKIGQLR HRLLATQSSR HLPALPAADD TGQLQVSAFG LDITKEDNGQ 
4561:	IQVKPHESPS TSTPSSGEEA EVSPDEGTEH SEEQRPPSLI DLLGGEQAKK QAQERMEAQA 
4621:	AQQAAMSAIE AESKKAVQVP APSALSQVDL SQYTRRAVSF LARNFYNLKY VALVLAFCIN 
4681:	FVLLFYKVST LDVEGGEGSG IGDIIAAAAG SGSGSGSGSG DGGSGESDDA DDVIEVVHID 
4741:	EDFFYMEHVI KVAAAMHSVV SLAILIGYYH LKVPLAIFKR EKEIARKLEF DGLYIAEQPE 
4801:	DDDLKSHWDK LVISAKSFPV NYWDKFVKKK VRAKYSETYD FDSISNMLGM EKTSFTAQED 
4861:	EGSKGLINYI INIDWRYQVW KAGVTITDNS FLYSLWYFSF SVMGNFNNFF FAAHLLDVAV 
4921:	GFKTLRTILQ SVTHNGKQLV LTVMLLTIIV YIYTVIAFNF FRKFYVQEED DEVNRNCHDM 
4981:	LTCFVFNLYK GVRAGGGIGD ELEPPDGDDS EVYRIIFDIT FFFFIIVILL AILQGLIIDA 
5041:	FGRLRDQLES VKEDMESNCF ICGINKDYFD KVPHGFDTHV QREHNLANYM FFLMHLINKP 
5101:	DTEYTGQETY VWNMYTQRCW DFFPVGDCFR KQYEDLMGE