TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.8.10.11
Probable aquaporin TIP-type alpha (Alpha TIP) (Tonoplast intrinsic protein alpha)

Accession Number:P23958
Protein Name:Probable aquaporin TIP-type alpha
Length:256
Molecular Weight:27196.00
Species:Phaseolus vulgaris (Kidney bean) [3885]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate water

Cross database links:

Pfam: PF00230   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005774 C:vacuolar membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport
GO:0006833 P:water transport

References (2)

[1] “An intrinsic tonoplast protein of protein storage vacuoles in seeds is structurally related to a bacterial solute transporter (GlpF).”  Johnson K.D.et.al.   2152174
[2] “Tonoplast-bound protein kinase phosphorylates tonoplast intrinsic protein.”  Johnson K.D.et.al.   16653198

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MATRRYSFGR TDEATHPDSM RASLAEFAST FIFVFAGEGS GLALVKIYQD SAFSAGELLA 
61:	LALAHAFALF AAVSASMHVS GGHVNPAVSF GALIGGRISV IRAVYYWIAQ LLGSIVAALV 
121:	LRLVTNNMRP SGFHVSPGVG VGHMFILEVV MTFGLMYTVY GTAIDPKRGA VSYIAPLAIG 
181:	LIVGANILVG GPFDGACMNP ALAFGPSLVG WQWHQHWIFW VGPLLGAALA ALVYEYAVIP 
241:	IEPPPHHHQP LATEDY