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1.A.8.10.5
Endoplasmic reticulum Small and Basic Intrinsic Protein; (SIP1;1) water channel (present in all plant tissues except seeds) (Ishikawa et al., 2005) May play a role in gas and water exchange between the plant and its environment via stromata (turgor-driven epidermal valves) and the hydathode pore (Pillitteri et al., 2008).

Accession Number:Q9M8W5
Protein Name:Aquaporin SIP1-1
Length:240
Molecular Weight:25706.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate water, CO2

Cross database links:

Genevestigator: Q9M8W5
eggNOG: KOG0223
HEGENOM: HBG318105
RefSeq: NP_187059.1   
Entrez Gene ID: 819564   
Pfam: PF00230   
KEGG: ath:AT3G04090   

Gene Ontology

GO:0005789 C:endoplasmic reticulum membrane
GO:0016021 C:integral to membrane
GO:0015250 F:water channel activity
GO:0006810 P:transport

References (3)

[1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[2] “From genome to function: the Arabidopsis aquaporins.”  Quigley F.et.al.   11806824
[3] “Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana.”  Ishikawa F.et.al.   16223486

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMGVLKSAIG DMLMTFSWVV LSATFGIQTA AIISAGDFQA ITWAPLVILT SLIFVYVSIF 
61:	TVIFGSASFN PTGSAAFYVA GVPGDTLFSL AIRLPAQAIG AAGGALAIME FIPEKYKHMI 
121:	GGPSLQVDVH TGAIAETILS FGITFAVLLI ILRGPRRLLA KTFLLALATI SFVVAGSKYT 
181:	GPAMNPAIAF GWAYMYSSHN TWDHIYVYWI SSFVGALSAA LLFRSIFPPP RPQKKKQKKA