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1.A.8.11.6
Aquaporin PIP2-8 (Plasma membrane intrinsic protein 2-8) (AtPIP2;8) (Plasma membrane intrinsic protein 3b) (PIP3b).  This protein as well as 1.A.8.11.4 are possibly orthologous to spinach PIP1;2 for which the crystal structure is available (PDP# 4JC6) (Berny et al. 2016).

Accession Number:Q9ZVX8
Protein Name:Probable aquaporin PIP2-8
Length:278
Molecular Weight:29500.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate water

Cross database links:

Genevestigator: Q9ZVX8
eggNOG: COG0580
HEGENOM: HOG000288286
Entrez Gene ID: 816186   
Pfam: PF00230   
KEGG: ath:AT2G16850   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0016020 C:membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0009737 P:response to abscisic acid stimulus
GO:0055085 P:transmembrane transport
GO:0006833 P:water transport

References (4)

[1] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.”  Lin X.et.al.   10617197
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “From genome to function: the Arabidopsis aquaporins.”  Quigley F.et.al.   11806824
[4] “Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.”  Reiland S.et.al.   19376835

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSKEVSEEGR HGKDYVDPPP APLLDMAELK LWSFYRAIIA EFIATLLFLY VTVATVIGHK 
61:	NQTGPCGGVG LLGIAWAFGG MIFVLVYCTA GISGGHINPA VTFGLFLARK VSLPRAVAYM 
121:	VAQCLGAICG VGLVKAFMMT PYKRLGGGAN TVADGYSTGT ALGAEIIGTF VLVYTVFSAT 
181:	DPKRSARDSH VPVLAPLPIG FAVFMVHLAT IPITGTGINP ARSFGAAVIY NNEKAWDDHW 
241:	IFWVGPFVGA LAAAAYHQYI LRAAAIKALA SFRSNPTN