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1.A.8.11.7
Aquaporin PIP2;5 (PIP2-5) of 285 aas.  Transports water and hydrogen peroxide (H2O2) (Bienert et al. 2014).  PIP1;2 doesn't transport H2O2.  TMS3 contains an LxxA motif that targets the protein to the plasma membrane from the ER.  While PIP2s are in the plasma mebrane, PIP1s are retained in the ER; this motif only partly explains the difference (Chevalier and Chaumont 2015).  PIP1;2 AND PIP2;5 form homo- and heterotetramers (Berny et al. 2016).

Accession Number:Q9XF58
Protein Name:Aquaporin PIP2-5
Length:285
Molecular Weight:29836.00
Species:Zea mays (Maize) [4577]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate water, H2O2

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAKDIEAAAA HEGKDYSDPP PAPLVDAEEL TKWSLYRAVI AEFVATLLFL YITVATVIGY 
61:	KHQTDAAASG PDAACGGVGV LGIAWAFGGM IFILVYCTAG VSGGHINPAV TFGLFLARKV 
121:	SLVRALLYIV AQCLGAICGV GLVKGFQSAF YVRYGGGANE LSAGYSKGTG LAAEIIGTFV 
181:	LVYTVFSATD PKRNARDSHV PVLAPLPIGF AVFMVHLATI PITGTGINPA RSLGAAVIYN 
241:	NDKAWDDHWI FWVGPFIGAA IAAAYHQYVL RASAAKLGSS ASFSR