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1.A.8.12.3
The boric acid channel protein, NIP5;1 (expressed in the root elongation zone and root hairs in response to boron deficiency) (Takano et al., 2006)

Accession Number:Q9SV84
Protein Name:Probable aquaporin NIP5-1
Length:304
Molecular Weight:31493.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Boric acid

Cross database links:

Genevestigator: Q9SV84
HEGENOM: HBG705794
RefSeq: NP_192776.1   
Entrez Gene ID: 826630   
Pfam: PF00230   
KEGG: ath:AT4G10380   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015105 F:arsenite transmembrane transporter activity
GO:0046715 F:boron transmembrane transporter activity
GO:0080138 F:boron uptake transmembrane transporter acti...
GO:0015250 F:water channel activity
GO:0015700 P:arsenite transport
GO:0046713 P:boron transport
GO:0080029 P:cellular response to boron levels
GO:0046685 P:response to arsenic

References (3)

[1] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.”  Mayer K.F.X.et.al.   10617198
[2] “From genome to function: the Arabidopsis aquaporins.”  Quigley F.et.al.   11806824
[3] “The Arabidopsis major intrinsic protein NIP5;1 is essential for efficient boron uptake and plant development under boron limitation.”  Takano J.et.al.   16679457

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAPPEAEVGA VMVMAPPTPG TPGTPGGPLI TGMRVDSMSF DHRKPTPRCK CLPVMGSTWG 
61:	QHDTCFTDFP SPDVSLTRKL GAEFVGTFIL IFTATAGPIV NQKYDGAETL IGNAACAGLA 
121:	VMIIILSTGH ISGAHLNPSL TIAFAALRHF PWAHVPAYIA AQVSASICAS FALKGVFHPF 
181:	MSGGVTIPSV SLGQAFALEF IITFILLFVV TAVATDTRAV GELAGIAVGA TVMLNILVAG 
241:	PSTGGSMNPV RTLGPAVASG NYRSLWVYLV APTLGAISGA AVYTGVKLND SVTDPPRPVR 
301:	SFRR