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1.A.8.12.7
Aquaporin NIP1-2 (NOD26-like intrinsic protein 1-2) (AtNIP1;2) (Nodulin-26-like major intrinsic protein 2) (NodLikeMip2) (Protein NLM2)

Accession Number:Q8LFP7
Protein Name:Aquaporin NIP1-2
Length:294
Molecular Weight:31269.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate water

Cross database links:

Genevestigator: Q8LFP7
eggNOG: COG0580
HEGENOM: HOG000288286
Entrez Gene ID: 827626   
Pfam: PF00230   
KEGG: ath:AT4G18910   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015105 F:arsenite transmembrane transporter activity
GO:0080170 P:hydrogen peroxide transmembrane transport
GO:0046685 P:response to arsenic-containing substance
GO:0006833 P:water transport

References (5)

[1] “Functional identification of the glycerol permease activity of Arabidopsis thaliana NLM1 and NLM2 proteins by heterologous expression in Saccharomyces cerevisiae.”  Weig A.R.et.al.   11007982
[2] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.”  Mayer K.F.X.et.al.   10617198
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “From genome to function: the Arabidopsis aquaporins.”  Quigley F.et.al.   11806824
[5] “Temporal analysis of sucrose-induced phosphorylation changes in plasma membrane proteins of Arabidopsis.”  Niittylae T.et.al.   17586839

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAEISGNGGD ARDGAVVVNL KEEDEQQQQQ QAIHKPLKKQ DSLLSISVPF LQKLMAEVLG 
61:	TYFLIFAGCA AVAVNTQHDK AVTLPGIAIV WGLTVMVLVY SLGHISGAHF NPAVTIAFAS 
121:	CGRFPLKQVP AYVISQVIGS TLAAATLRLL FGLDQDVCSG KHDVFVGTLP SGSNLQSFVI 
181:	EFIITFYLMF VISGVATDNR AIGELAGLAV GSTVLLNVII AGPVSGASMN PGRSLGPAMV 
241:	YSCYRGLWIY IVSPIVGAVS GAWVYNMVRY TDKPLREITK SGSFLKTVRN GSSR