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1.A.8.12.9
Aquaporin NIP6-1 (NOD26-like intrinsic protein 6-1) (AtNIP6;1)

Accession Number:Q9SAI4
Protein Name:Aquaporin NIP6-1
Length:305
Molecular Weight:31845.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate water

Cross database links:

Genevestigator: Q9SAI4
eggNOG: COG0580
HEGENOM: HOG000288286
Entrez Gene ID: 844415   
Pfam: PF00230   
KEGG: ath:AT1G80760   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0046715 F:borate transmembrane transporter activity
GO:0015168 F:glycerol transmembrane transporter activity
GO:0015204 F:urea transmembrane transporter activity
GO:0080029 P:cellular response to boron-containing substance levels

References (3)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “From genome to function: the Arabidopsis aquaporins.”  Quigley F.et.al.   11806824
[3] “Distinct transport selectivity of two structural subclasses of the nodulin-like intrinsic protein family of plant aquaglyceroporin channels.”  Wallace I.S.et.al.   16363796

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDHEEIPSTP STPATTPGTP GAPLFGGFEG KRNGHNGRYT PKSLLKSCKC FSVDNEWALE 
61:	DGRLPPVTCS LPPPNVSLYR KLGAEFVGTL ILIFAGTATA IVNQKTDGAE TLIGCAASAG 
121:	LAVMIVILST GHISGAHLNP AVTIAFAALK HFPWKHVPVY IGAQVMASVS AAFALKAVFE 
181:	PTMSGGVTVP TVGLSQAFAL EFIISFNLMF VVTAVATDTR AVGELAGIAV GATVMLNILI 
241:	AGPATSASMN PVRTLGPAIA ANNYRAIWVY LTAPILGALI GAGTYTIVKL PEEDEAPKER 
301:	RSFRR