TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.8.2.2
Mixed function glycerol facilitator/aquaporin, GlpF (Froger et al. 2001).

Accession Number:P22094
Protein Name:YDP1 aka GLA aka GlpF
Length:289
Molecular Weight:30935.00
Species:Lactococcus lactis (subsp [1359]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate water, glycerol

Cross database links:

Pfam: PF00230   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006071 P:glycerol metabolic process
GO:0006810 P:transport

References (3)

[1] “Molecular cloning and sequence analysis of the X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. cremoris.”  Mayo B.et.al.   1674655
[2] “Cloning and DNA sequence analysis of an X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. lactis NCDO 763.”  Nardi M.et.al.   1674656
[3] “Functional characterization of a microbial aquaglyceroporin.”  Froger A.et.al.   11320116

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MDVTWTVKYI TEFVGTALLI IMGNGAVANV ELKGTKAHAQ SWMIIGWGYG LGVMLPAVAF 
61:	GNITSQINPA FTLGLAASGL FPWAHVAQYI IAQVLGAMFG QLLIVMVYRP YYLKTQNPNA 
121:	ILGTFSTIDN VDDNSEKTRL GATINGFLNE FLGSFVLFFG AVAATNIFFG SQSITWMTNY 
181:	LKGQGADVSS SDVMNQIWVQ ASGASASKMI AHLFLGFLVM GLVVALGGPT GPGLNPARDF 
241:	GPRLVHSLLP KSVLGEAKGS SKWWYAWVPV LAPILASLAA VALFKMIYL