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1.A.8.8.14
Lens fiber major intrinsic protein (MIP26) (MP26)

Accession Number:Q06019
Protein Name:Lens fiber major intrinsic protein
Length:263
Molecular Weight:28383.00
Species:Rana pipiens (Northern leopard frog) [8404]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

Pfam: PF00230   

Gene Ontology

GO:0005921 C:gap junction
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005212 F:structural constituent of eye lens
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport
GO:0006833 P:water transport

References (1)

[1] “The cDNA sequence encoding the major intrinsic protein of frog lens.”  Austin L.R.et.al.   7916707

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MWEFRSFSFW RAVFAEFFGT MFYVFFGLGA SLKWAAGPAN VLVIALAFGL VLATMVQSIG 
61:	HVSGAHINPA VTFAFLIGSQ MSLFRAIFYI AAQLLGAVAG AAVLYGVTPA AIRGNLALNT 
121:	LHPGVSLGQA TTVEIFLTLQ FVLCIFATYD ERRNGRLGSV SLAIGFSLTL GHLFGLYYTG 
181:	ASMNPARSFA PAVLTRNFTN HWVYWVGPII GGALGGLVYD FILFPRMRGL SERLSILKGA 
241:	RPAEPEGQQE ATGEPIELKT QSL