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1.A.8.9.13
Aquaglycerolporin, Aqp (high permeability to ammonium, methylamine, glycerol and water) (Beitz et al., 2004) NH4+/NH3+CH3 transporter (Zeuthen et al., 2006).

Accession Number:Q8WPZ6
Protein Name:Aquaglyceroporin
Length:258
Molecular Weight:28297.00
Species:Plasmodium falciparum [5833]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Ammonium, Methylamine, glycerol, water, ammonia

Cross database links:

eggNOG: KOG0224
DIP: DIP-46381N
Pfam: PF00230   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “A single, bi-functional aquaglyceroporin in blood-stage Plasmodium falciparum malaria parasites.”  Hansen M.et.al.   11729204
Structure:
3C02     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MHMLFYKSYV REFIGEFLGT FVLMFLGEGA TANFHTTGLS GDWYKLCLGW GLAVFFGILV 
61:	SAKLSGAHLN LAVSIGLSSI NKFDLKKIPV YFFAQLLGAF VGTSTVYGLY HGFISNSKIP 
121:	QFAWETSRNP SISLTGAFFN ELILTGILLL VILVVVDENI CGKFHILKLS SVVGLIILCI 
181:	GITFGGNTGF ALNPSRDLGS RFLSLIAYGK DTFTKDNFYF WVPLVAPCVG SVVFCQFYDK 
241:	VICPLVDLAN NEKDGVDL