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1.A.8.9.4
Aquaporin 1 (permeable to water, glycerol, dihydroxyacetone and urea) (Uzcategui et al., 2004)

Accession Number:Q6ZXT4
Protein Name:Aquaglyceroporin 1
Length:321
Molecular Weight:35040.00
Species:Trypanosoma brucei brucei [5702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate water, glycerol, Dihydroxyacetone, Urea

Cross database links:

Pfam: PF00230   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei.”  Uzcategui N.L.et.al.   15294911

External Searches:

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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSDEKINVHQ YPSEADVRGL KARNGGACEV PFEENNEPIP NRSANPQEKN ENELVGDNAD 
61:	NEAHDAVDVN YWAPRQLRLD YRNYMGEFLG TFVLLFMGNG VVATTILDKD LGFLSIAFGW 
121:	GIAVTMGLYI SLGISCGHLN PAVTLANAVF GCFPWRRVPG YIAAQMLGAF VGAACAYGVY 
181:	ADLLKQHSGG LVGFGDKGFA GMFSTYPREG NRLFYCIFSE FICTAILLFC VGGIFDPNNS 
241:	PAKGHEPLAV GALVFAIGNN IGYASGYAIN PARDFGPRVF SAILFGSEVF TTGNYYFWVP 
301:	LFIPFLGGIF GLFLYKYFVP Y